LncRNA AC006064.4-201 serves as a novel molecular marker in alleviating cartilage senescence and protecting against osteoarthritis by destabilizing CDKN1B mRNA via interacting with PTBP1.

Background: Osteoarthritis (OA) is the most prevalent age-related disease in the world. Chondrocytes undergo an age-dependent decline in their proliferation and synthetic capacity, which is the main cause of OA development. However, the intrinsic mechanism of chondrocyte senescence is still unclear.

Ground-State Phase Diagram of a Spin-Orbital-Angular-Momentum Coupled Bose-Einstein Condensate.

By inducing a Raman transition using a pair of Gaussian and Laguerre-Gaussian laser beams, we realize a ^{87}Rb condensate whose orbital angular momentum (OAM) and its internal spin states are coupled. By varying the detuning and the coupling strength of the Raman transition, we experimentally map out the ground-state phase diagram of the system for the first time. The transitions between different phases feature a discontinuous jump of the OAM and the spin polarization, and hence are of first order.

Multiple side-band generation for two-frequency components injected into a tapered amplifier.

We have experimentally studied multiple side-band generation for two-frequency components injected into a tapered amplifier (TA) and demonstrated its effects on atomic laser cooling. A heterodyne frequency-beat measurement and a Fabry-Perot interferometer have been applied to analyze the side-band generation with different experimental parameters, such as frequency difference, injection laser power, and TA current. In laser-cooling potassium40 and potassium41 with hyperfine splitting of 1.