miR-155 promotes fibroblast-like synoviocyte proliferation and inflammatory cytokine secretion in rheumatoid arthritis by targeting FOXO3a.

The present study aimed to explore the expression and effects of microRNA (miR)-155 in synovial fibroblasts of patients with rheumatoid arthritis (RA). A total of 89 synovial tissues from RA patients and 49 control synovial tissues were collected, and the levels of miR-155 were measured by reverse transcription quantitative-PCR and western blotting. Fibroblast-like synoviocytes (FLS) were isolated from synovial tissues from the control group and were used to evaluate the roles of miR-155 and forkhead box protein O3a (FOXO3a).

Subtraction CT angiography for the detection of intracranial aneurysms: A meta-analysis.

The aim of this meta-analysis was to investigate the accuracy of subtraction computed tomography angiography (CTA) for diagnosing intracranial aneurysms. A systematic literature search up to January 1, 2013 was performed in PubMed. Two independent reviewers selected 8 studies that compared subtraction CTA with digital subtraction angiography.

Associations between Lectin-like, oxidized low-density lipoprotein receptor-1 G501C and 3'-UTR-C188T polymorphisms with coronary artery disease: a meta-analysis.

Unlabelled: The background and purpose: Published data on the association between LOX-1 3'UTR C188T and G501C polymorphisms with coronary artery disease (CAD) risk are inconclusive. In order to derive a more precise estimation of the relationship, a meta-analysis was conducted.

Methods And Subjects: Crude ORs with 95% CIs were used to assess the strength of association between these polymorphisms and CAD risk.

Parachute mitral valve accompanied by bicuspid aortic valve on three-dimensional transesophageal echocardiography.

We report the findings of three-dimensional (3D) transesophageal echocardiography (TEE) in a patient with a parachute mitral valve (MV) accompanied by aortic valve (AV) malformation. The results indicated an enhanced echo in MV anterior leaves, incrassate, and shortened subvalvular chordae tendineae, and posteromedial papillary muscle that had echo reinforcement, calcification, retroposition, and a significant decrease compared with anterolateral papillary muscle. In addition, the anterolateral papillary muscle was huge, with the bilateral papillary muscles fused partly, and the posterior subvalvular chordae tendineae incrassate, shortened, and attached parachute-like to the anterolateral papillary muscle.

Large, isolated aortic valve aneurysm: detected on real-time 3-dimensional echocardiography.

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