Comparison of Accuracy in Mandible-First and Maxilla-First Approaches in Bimaxillary Orthognathic Surgery: A Meta-Analysis.

This meta-analysis compares the accuracy of mandible-first and maxilla-first approaches in bimaxillary orthognathic surgery to improve clinical decision-making. A systematic search was performed in PubMed, Web of Science, Embase, and Cochrane databases up to August 2024. The analysis included randomized controlled trials and cohort studies with a minimum of 10 patients.

TiCT Composite Aerogels Enable Pressure Sensors for Dialect Speech Recognition Assisted by Deep Learning.

Wearable pressure sensors capable of adhering comfortably to the skin hold great promise in sound detection. However, current intelligent speech assistants based on pressure sensors can only recognize standard languages, which hampers effective communication for non-standard language people. Here, we prepare an ultralight TiCT MXene/chitosan/polyvinylidene difluoride composite aerogel with a detection range of 6.

A Safe and Convenient Method to Isolate Bone Marrow Mononuclear Cells in Clinical Practice.

Background: Bone marrow mononuclear cells (BMMNCs) are becoming a promising cell therapy in regeneration medicine. BMMNCs are now obtained by density gradient centrifugation (DGC) in clinical practice, which is complicated and greatly influenced by human manipulation.

Objective: Our objective is to develop a simple and safe method to isolate BMMNCs.

TiCT Aerogel-Based Wearable Humidity Sensors with Low Hysteresis and High Linearity for Expiratory Comfort Management.

Wearable and flexible humidity sensors hold great promise for expiratory comfort management. However, the high hysteresis and poor detection linearity restrict the immediate and accurate detection of humidity. Herein, we have prepared TiCT MXene/chitosan/polyvinylidene difluoride aerogels with a controllable hydrophobic/hydrophilic surface to regulate the catch/escape behavior of HO molecules.

Study of the ability of polysaccharides isolated from Zizania latifolia to promote wound healing in mice via in vitro screening and in vivo evaluation.

Swollen culms of Zizania latifolia possess a peculiar flavor, nutritional value and health-promoting effects. This study investigated the wound healing ability of polysaccharides isolated from Zizania latifolia (ZLP). Through in vitro assays, ZLP demonstrated negligible cytotoxicity and promoted the migration and phagocytosis of Staphylococcus aureus by macrophages where ZLP-2 had a significantly greater effect.

The Metabolic Characteristics and Bioavailability of Resveratrol Based on Metabolic Enzymes.

The natural polyphenol resveratrol (RV) has garnered fame for its extensive pharmacological properties. Although clinical studies have shown some positive results, many contradictory outcomes remain. An important obstacle to the development of therapeutic applications for RV is its low bioavailability in vivo.

Intersubject Dynamic Conditional Correlation: A Novel Method to Track the Framewise Network Implication during Naturalistic Stimuli.

Naturalistic stimuli have become increasingly popular in modern cognitive neuroscience. These stimuli have high ecological validity due to their rich and multilayered features. However, their complexity also presents methodological challenges for uncovering neural network reconfiguration.

Integrated Mixed Potential Gas Sensor with Efficient Structure for Discriminative Volatile Organic Compounds Detection.

Amid growing interest in the precise detection of volatile organic compounds (VOCs) in industrial field, the demand for highly effective gas sensors is at an all-time high. However, traditional sensors with their classic single-output signal, bulky and complex integrated structure when forming array often involve complicated technology and high cost, limiting their widespread adoption. Here, this study introduces a novel approach, employing an integrated YSZ-based (YSZ: yttria-stabilized zirconia) mixed potential sensor equipped with a triple-sensing electrode array, to efficiently detect and differentiate six types of VOCs gases.

Neutrophil extracellular traps-inspired DNA hydrogel for wound hemostatic adjuvant.

Severe traumatic bleeding may lead to extremely high mortality rates, and early intervention to stop bleeding plays as a critical role in saving lives. However, rapid hemostasis in deep non-compressible trauma using a highly water-absorbent hydrogel, combined with strong tissue adhesion and bionic procoagulant mechanism, remains a challenge. In this study, a DNA hydrogel (DNAgel) network composed of natural nucleic acids with rapid water absorption, high swelling and instant tissue adhesion is reported, like a band-aid to physically stop bleeding.

Multilayer Fluorine-Free MoBT MBene with Hydrophilic Structural-Modulating for the Fabrication of a Low-Resistance and High-Resolution Humidity Sensor.

2D transition metal borides (MBenes) with abundant surface terminals hold great promise in molecular sensing applications. However, MBenes from etching with fluorine-containing reagents present inert -fluorine groups on the surface, which hinders their sensing capability. Herein, the multilayer fluorine-free MoBT MBene (where T represents O, OH, and Cl) with hydrophilic structure is prepared by a hydrothermal-assisted hydrochloric acid etching strategy based on guidance from the first-principle calculations.

Effect of Hot-Pressing Process on Mechanical Properties of UHMWPE Fiber Non-Woven Fabrics.

In order to investigate the influence of a hot-pressing process on the mechanical properties of ultra-high molecular weight polyethylene (UHMWPE) fiber non-woven fabrics with stretch and in-plane shear, UHMWPE non-woven fabric samples were prepared by adjusting the temperature, time, and pressure of the hot-pressing process, and mechanical property tests were carried out so as to clarify the influence of the hot-pressing process on the mechanical properties of the samples. The results show that the hot-pressing process mainly affects the silk-glue bonding strength of the samples; in the test range, with the increase in hot-pressing temperature and time, the tensile strength and in-plane shear strength of the samples increase and then decrease, and the best mechanical properties are obtained at 130 °C and 7 min of hot pressing, respectively; at 130 °C, the in-plane shear strength is 39.94 MPa and the tensile strength is 595.

Multi-cohort comprehensive analysis unveiling the clinical value and therapeutic effect of in glioma.

Clinical data indicates that glioma patients have poor treatment outcomes and clinical prognosis. The role of olfactory signaling pathway-related genes (OSPRGs) in glioma has not been fully elucidated. In this study, we aimed to investigate the role and relationship between OSPRGs and glioma.

Modeling the precise interaction of glioblastoma with human brain region-specific organoids.

Glioblastoma is a highly aggressive malignant tumor of the central nervous system, but the interaction between glioblastoma and different types of neurons remains unclear. Here, we established a co-culture model using 3D printed molds with microchannels, in which glioblastoma organoids (GB), dorsal forebrain organoids (DO, mainly composed of excitatory neurons), and ventral forebrain organoids (VO, mainly composed of inhibitory neurons) were assembled. Our results indicate that DO has a greater impact on altered gene expression profiles of GB, resulting in increased invasive potential.

The Impact of Centrifugal Force on Isolation of Bone Marrow Mononuclear Cells Using Density Gradient Centrifugation.

Background: Bone marrow mononuclear cells (BMMNCs) have great potential in bone regenerative therapy. The main method used today to obtain BMMNCs is Ficoll density gradient centrifugation. However, the centrifugal force for this isolation method is still suboptimal.

An active derivatization detection method for inline monitoring the isolation of carbohydrates by preparative liquid chromatography.

Polysaccharides have unique physio-chemical properties and various biological functions and have rapidly expanded interest over the last two decades. The purification of polysaccharides and their degraded oligosaccharides is challenging because carbohydrates have no chromophore and need a proper detector to monitor the chromatographic elution process. This study proposed an active derivatization detection (ADD) method based on active splitting from post-column flow, a microchannel reactor for efficient derivatization of polysaccharide reducing sugars with p-hydroxybenzoic acid hydrazide, and in-line detection by the UV detector of liquid chromatography system.

Five Retained Soft Contact Lenses in the Upper Fornix: A Case Report in a Patient with Hemifacial Atrophy.

The displacement of a lost contact lens into the upper fornix is an uncommon occurrence. This case report presents a rare incidence wherein a patient diagnosed with hemifacial atrophy was found to have concealed five soft contact lenses within the left upper fornix during autologous fat injection into the retrobulbar space.

Extraction, structure, pharmacological activities and applications of polysaccharides and proteins isolated from snail mucus.

Snail mucus had medical applications for wound healing as early as ancient Greece and the late Han Dynasty (China). A literature search found 165 modern research papers discussing the extraction methods, chemical compositions, pharmacological activities, and applications of snail mucus. Thus, this review summarized the research progress on the extraction, structure, pharmacological activities, and applications of polysaccharides and proteins isolated from snail mucus.

Anti-sagging Method in Reduction Malarplasty: Application of the Bracing System with the Preservation of the Zygomaticus Major Muscle Bony Attachment.

Background: Cheek drooping after reduction malarplasty remains a concern for patients.

Objectives: To evaluate the anti-drooping effectiveness of the bracing system technique with the preservation of the zygomaticus major muscle (ZMj) bony attachment and to determine the role of ZMj in anti-drooping.

Methods: A retrospective analysis was conducted of patients who accepted this method in our department from February 2016 to May 2021.

Pattern Recognition with Temperature Regulation: A Single YSZ-Based Mixed Potential Sensor Classifies Multiple Mixtures of Isoprene, -Propanol, and Acetone.

Gas sensors integrated with machine learning algorithms have aroused keen interest in pattern recognition, which ameliorates the drawback of poor selectivity on a sensor. Among various kinds of gas sensors, the yttria-stabilized zirconia (YSZ)-based mixed potential-type sensor possesses advantages of low cost, simple structure, high sensitivity, and superior stability. However, as the number of sensors increases, the increased power consumption and more complicated integration technology may impede their extensive application.

A Surgical Management Algorithm for Type 4 Parry-Romberg Syndrome.

Background: Type 4 Parry-Romberg syndrome (PRS) affects multiple facial esthetic units involving many tissue types, requiring both bone and soft tissue restoration and requiring different surgical procedures over a long period of time. To date, the timing and sequence of these operations remains controversial.

Methods: A retrospective analysis was performed to introduce our surgical management algorithm for type 4 PRS and to evaluate its safety and efficacy according to long-term follow-up results.