Achieving a Thermodynamic Self-Regulation Dynamic Adsorption Mechanism for Ammonia Synthesis through Selective Orbital Coupling.

With the continuous pursuing on the improvement of catalytic activity, a catalyst performed exceeding catalytic volcano plots is desired, while it is impeded by the adsorption-energy scaling relations of reaction intermediates. Numerous efforts have been focused on optimizing the initial and final intermediates to circumvent the scaling relations for an improved performance. For a step forward, simultaneously optimizing all intermediates is essential to explore the theoretical maximum of catalytic activity.

Dual-Intermetallic Heterostructure on Hierarchical Nanoporous Metal for Highly Efficient Alkaline Hydrogen Electrocatalysis.

Constructing well-defined active multisites is an effective strategy to break linear scaling relationships to develop high-efficiency catalysts toward multiple-intermediate reactions. Here, dual-intermetallic heterostructure composed of tungsten-bridged CoW and WNi intermetallic compounds seamlessly integrated on hierarchical nanoporous nickel skeleton is reported as a high-performance nonprecious electrocatalyst for alkaline hydrogen evolution and oxidation reactions. By virtue of interfacial tungsten atoms configuring contiguous multisites with proper adsorptions of hydrogen and hydroxyl intermediates to accelerate water dissociation/combination and column-nanostructured nickel skeleton facilitating electron and ion/molecule transportations, nanoporous nickel-supported CoW-WNi heterostructure exhibits exceptional hydrogen electrocatalysis in alkaline media, with outstanding durability and impressive catalytic activities for hydrogen oxidation reaction (geometric exchange current density of ≈6.

Glycated Walnut Meal Peptide-Calcium Chelates: Preparation, Characterization, and Stability.

Finding stable and bioavailable calcium supplements is crucial for addressing calcium deficiency. In this study, glycated peptide-calcium chelates (WMPHs-COS-Ca) were prepared from walnut meal protein hydrolysates (WMPHs) and chitosan oligosaccharides (COSs) through the Maillard reaction, and the structural properties and stability of the WMPHs-COS-Ca were characterized. The results showed that WMPHs and COSs exhibited high binding affinities, with a glycation degree of 64.

Lamellar Nanoporous Metal/Intermetallic Compound Heterostructure Regulating Dendrite-Free Zinc Electrodeposition for Wide-Temperature Aqueous Zinc-Ion Battery.

Aqueous zinc-ion batteries are attractive post-lithium battery technologies for grid-scale energy storage because of their inherent safety, low cost and high theoretical capacity. However, their practical implementation in wide-temperature surroundings persistently confronts irregular zinc electrodeposits and parasitic side reactions on metal anode, which leads to poor rechargeability, low Coulombic efficiency and short lifespan. Here, this work reports lamellar nanoporous Cu/AlCu heterostructure electrode as a promising anode host material to regulate high-efficiency and dendrite-free zinc electrodeposition and stripping for wide-temperatures aqueous zinc-ion batteries.

In Situ Engineering Multifunctional Active Sites of Ruthenium-Nickel Alloys for pH-Universal Ampere-Level Current-Density Hydrogen Evolution.

Developing robust non-platinum electrocatalysts with multifunctional active sites for pH-universal hydrogen evolution reaction (HER) is crucial for scalable hydrogen production through electrochemical water splitting. Here ultra-small ruthenium-nickel alloy nanoparticles steadily anchored on reduced graphene oxide papers (Ru-Ni/rGOPs) as versatile electrocatalytic materials for acidic and alkaline HER are reported. These Ru-Ni alloy nanoparticles serve as pH self-adaptive electroactive species by making use of in situ surface reconstruction, where surface Ni atoms are hydroxylated to produce bifunctional active sites of Ru-Ni(OH) for alkaline HER, and selectively etched to form monometallic Ru active sites for acidic HER, respectively.

Physical and Chemical Properties, Flavor and Organoleptic Characteristics of a Walnut and Purple Rice Fermented Plant Drink.

In recent years, green and healthy foods have attracted much attention. Plant-based foods have become an alternative to animal-derived foods. In this study, we used walnut and purple rice as the primary raw materials to produce a fermented plant drink.

Dendrobium officinale Kinura et Migo glycoprotein promotes skin wound healing by regulating extracellular matrix secretion and fibroblast proliferation on the proliferation phase.

Dendrobium officinale Kinura et Migo (DOKM) has a variety of medicinal applications; however, its ability to promote wound healing has not been previously reported. The purpose of this study is to investigate the proliferative phase of the wound-healing effect of DOKM glycoprotein (DOKMG) in rats and to elucidate its mechanism of action in vitro. In the present study, the ointment mixture containing DOKMG was applied to the dorsal skin wounds of the full-thickness skin excision rat model, and the results showed that the wound healing speed was faster in the proliferative phase than vaseline.

Heterostructured Co-Doped-CuO/Cu Synergistically Promotes Water Dissociation for Improved Electrochemical Nitrate Reduction to Ammonia.

Electrochemical nitrate reduction reaction (NORR) has recently emerged as a promising approach for sustainable ammonia synthesis and wastewater treatment, while the activity and selectivity for ammonia production have remained low. Herein, rational design and controllable synthesis of heterostructured Co-doped CuO/Cu nanoparticles embedded in carbon framework (Co-CuO/Cu@C) is reported for NORR. The Co-CuO/Cu@C exhibits a high ammonia yield rate of 37.

Gram-level NH Electrosynthesis via NO reduction on a Cu Activated Co Electrode.

Ambient electrochemical ammonia (NH ) synthesis is one promising alternative to the energy-intensive Haber-Bosch route. However, the industrial requirement for the electrochemical NH production with amperes current densities or gram-level NH yield remains a grand challenge. Herein, we report the high-rate NH production via NO reduction using the Cu activated Co electrode in a bipolar membrane (BPM) assemble electrolyser, wherein BPM maintains the ion balance and the liquid level of electrolyte.

A Bifunctional Catalyst for Green Ammonia Synthesis from Ubiquitous Air and Water.

Ammonia (NH ) is essential for modern agriculture and industry, and, due to its high hydrogen density and no carbon emission, it is also expected to be the next-generation of "clean" energy carrier. Herein, directly from air and water, a plasma-electrocatalytic reaction system for NH production, which combines two steps of plasma-air-to-NO and electrochemical NO reduction reaction (eNO RR) with a bifunctional catalyst, is successfully established. Especially, the bifunctional catalyst of CuCo O /Ni can simultaneously promote plasma-air-to-NO and eNO RR processes.

Achieving volatile potassium promoted ammonia synthesis via mechanochemistry.

Potassium oxide (KO) is used as a promotor in industrial ammonia synthesis, although metallic potassium (K) is better in theory. The reason KO is used is because metallic K, which volatilizes around 400 °C, separates from the catalyst in the harsh ammonia synthesis conditions of the Haber-Bosch process. To maximize the efficiency of ammonia synthesis, using metallic K with low temperature reaction below 400 °C is prerequisite.

Lamella-heterostructured nanoporous bimetallic iron-cobalt alloy/oxyhydroxide and cerium oxynitride electrodes as stable catalysts for oxygen evolution.

Developing robust nonprecious-metal electrocatalysts with high activity towards sluggish oxygen-evolution reaction is paramount for large-scale hydrogen production via electrochemical water splitting. Here we report that self-supported laminate composite electrodes composed of alternating nanoporous bimetallic iron-cobalt alloy/oxyhydroxide and cerium oxynitride (FeCo/CeON) heterolamellas hold great promise as highly efficient electrocatalysts for alkaline oxygen-evolution reaction. By virtue of three-dimensional nanoporous architecture to offer abundant and accessible electroactive CoFeOOH/CeON heterostructure interfaces through facilitating electron transfer and mass transport, nanoporous FeCo/CeON composite electrodes exhibit superior oxygen-evolution electrocatalysis in 1 M KOH, with ultralow Tafel slope of ~33 mV dec.

The development of catalysts for electrochemical nitrogen reduction toward ammonia: theoretical and experimental advances.

Ammonia (NH) is essential for the industrial production of fertilizers, pharmaceuticals, plastics, synthetic fibers, resins, and chemicals, and it is also a promising carbon-free energy carrier. The electrocatalytic nitrogen reduction reaction (eNRR) driven by renewable energy sources at ambient temperature and atmospheric pressure is an alternative approach to the Haber-Bosch process for NH synthesis. However, the efficient electrocatalytic reduction of nitrogen (N) to NH is challenging due to the lack of effective electrocatalysts.

Tailoring Electronic Structure of Copper Twin Boundaries Toward Highly Efficient Nitrogen Reduction Reaction.

Electrocatalytic nitrogen reduction reaction (NRR) is a promising technique to resolve the carbon emission in energy-intensive ammonia production in industry, which, however, is hampered by the lack of efficient catalysts. Herein, by density functional theory (DFT) calculations, it was demonstrated that the twin boundary (TB) of copper could effectively relieve the N activation barrier in NRR. The d orbitals overlapping mode on twin boundary edge (TBE) was quite different from that on its basal plane, where the d , d orbitals induced unbalanced electron occupation states in π*-p , p orbitals of the adsorbed N , which could effectively activate the N≡N bond.

miR-29c-5p knockdown reduces inflammation and blood-brain barrier disruption by upregulating LRP6.

Blood-brain barrier participates in the pathological process of ischemic stroke. MicroRNA-29c-5p was highly expressed in clinical samples from patients with ischemic stroke. In this study, oxygen-glucose deprivation (OGD) treatment of astrocytes enhanced the permeability of brain microvascular endothelial cells (BMECs), and the miR-29c-5p expression was elevated in clinical samples from patients with ischemic stroke.

Surface-Alloyed Nanoporous Zinc as Reversible and Stable Anodes for High-Performance Aqueous Zinc-Ion Battery.

Metallic zinc (Zn) is one of the most attractive multivalent-metal anode materials in post-lithium batteries because of its high abundance, low cost and high theoretical capacity. However, it usually suffers from large voltage polarization, low Coulombic efficiency and high propensity for dendritic failure during Zn stripping/plating, hindering the practical application in aqueous rechargeable zinc-metal batteries (AR-ZMBs). Here we demonstrate that anionic surfactant-assisted in situ surface alloying of Cu and Zn remarkably improves Zn reversibility of 3D nanoporous Zn electrodes for potential use as high-performance AR-ZMB anode materials.

Lambl's excrescence and the safety of radiofrequency ablation for atrial fibrillation.

Background: Lambl's excrescences (LEs) are excrescences with an extremely low incidence, mainly ultrasound diagnosed. Increasingly, LEs are detected by transesophageal echocardiography before catheter ablation, which raises safety concerns on whether LEs were associated with an embolism event during or after ablation, but clinical data are still lacking.

Methods And Results: We consecutively recruited 8081 patients with atrial fibrillation who underwent radiofrequency catheter ablation in Beijing Anzhen Hospital from Jan 1, 2017 to Dec 31, 2019.

Adhesive and high-sensitivity modified TiCT (MXene)-based organohydrogels with wide work temperature range for wearable sensors.

Hydrogel-based wearable sensors have gained great interest on account of their huge application in human-machine interfaces, electronic skin, and healthcare monitoring. However, there are still challenges in designing hydrogel-based sensors with high stability in a wide temperature range, superior adhesion, and excellent sensitivity. Herein, sensors based on oxidized sodium alginate (OSA)/polyacrylamide (PAm)/polydopamine-TiCT (PMXene) /glycerol/water (Gly/HO) organohydrogels were designed.

Urinary Proteomics for Noninvasive Prenatal Screening of Trisomy 21: New Biomarker Candidates.

Trisomy 21 is a common birth defect in humans. Screening for trisomy 21 is one of the most important tasks in routine prenatal care and robust noninvasive diagnostics are needed in clinical practice. Urinary proteomics offers a new research platform for diagnostics innovation in this context.

Short-Chain Fatty Acids Produced by Ruminococcaceae Mediate α-Linolenic Acid Promote Intestinal Stem Cells Proliferation.

Scope: The proliferation and differentiation of intestinal stem cells (ISCs) are the basis of intestinal renewal and regeneration, and gut microbiota plays an important role in it. Dietary nutrition has the effect of regulating the activity of ISCs; however, the regulation effect of α-linolenic acid (ALA) has seldom been reported.

Methods And Results: After intervening mice with different doses of ALA for 30 days, it is found that ALA (0.

Corrigendum: Alkaloids Inhibited PC3 Cells Growth and Migration Through the COX-2 Mediated Wnt/β-Catenin Signaling Pathway.

[This corrects the article DOI: 10.3389/fphar.2020.

Alkaloids Inhibited PC3 Cells Growth and Migration Through the COX-2 Mediated Wnt/β-Catenin Signaling Pathway.

Lam. () is valuable plant distributed in many tropical and subtropical countries. It has a number of medicinal uses and is highly nutritious.

Polyphenol Extract of Leaves Alleviates Colonic Inflammation in Dextran Sulfate Sodium-Treated Mice.

Lam. is an essential herb used for the treatment of inflammation, diabetes, high blood pressure, and other diseases. In this study, phenolic extracts of leaves were obtained and analyzed.