Endoscopic ultrasound-guided fine-needle aspiration and fine-needle biopsy in the diagnosis of gastrointestinal lymphomas.

Introduction: The role of endoscopic ultrasound-guided fine-needle aspiration and fine-needle biopsy (EUS-FNA/B) in the clinical management of gastrointestinal lymphoma has not been extensively studied. This study investigates the use of EUS-FNA/B in the diagnosis of first-time and recurrent gastrointestinal lymphomas at a large academic institution.

Materials And Methods: A total of 40 patients who had final diagnosis of lymphoma according to the World Health Organization (WHO) classification of tumors of hematopoietic lymphoid tissues who underwent EUS-FNA/B were included in the study.

Improvement of the reproducibility in LIBS single levitated aerosol particle analysis based on particle size-selectivity of photophoretic optical trap.

To improve the reproducibility of single particle analysis with LIBS, we study the particle size selectivity of photophoretic optical trap. Firstly, the photophoretic force is theoretically simulated and size selectivity in a Gaussian trapping beam is analyzed. Then, the particle size is statistically examined under different power of the trapping Gaussian beam.

Exposure to nanoplastics induces the elevation of Zn levels in cells as visualized by a Golgi apparatus-targetable ratiometric fluorescent nanosensor.

Nanoplastics are prevalent in the environment and emerging evidence suggests they can induce organ injury by activating oxidative stress. Given that both nanoplastics and Zn levels are intertwined with oxidative stress, it is crucial to investigate the influence of nanoplastics on the level of labile Zn and get a better understanding of their cytotoxicity mechanisms. At the organelle level, the Golgi apparatus plays an active role in stress responses.

[Research progress on the identification of central lung cancer and atelectasis using multimodal imaging].

Central lung cancer is a common disease in clinic which usually occurs above the segmental bronchus. It is commonly accompanied by bronchial stenosis or obstruction, which can easily lead to atelectasis. Accurately distinguishing lung cancer from atelectasis is important for tumor staging, delineating the radiotherapy target area, and evaluating treatment efficacy.

HMGB1 in Systemic Lupus Erythematosus.

The high-mobility group box 1 (HMGB1) has been shown to exert proinflammatory effects on many cells of the innate immune system. Originally identified as a nuclear protein, HMGB1 has been found to play an important role in mediating inflammation when released from apoptotic or necrotic cells as a damage-associated molecular pattern (DAMP). Systemic lupus erythematosus (SLE) is a disease of non-resolving inflammation, characterized by the presence of autoantibodies and systemic inflammation involving multiple organ systems.

Bio-inspired surface aberration mitigation technique for high-frequency conversion efficiency of large-aperture nonlinear optics.

Low-frequency conversion efficiency severely limits the 3ω ultraviolet energy density at the target of inertial confinement fusion facilities. Here, we present a bio-inspired surface aberration mitigation (SAM) technique that could significantly reduce the crystal surface aberration and realize high frequency conversion efficiency over a clear aperture of 400 mm × 400 mm. Numerical models are utilized to optimize and verify the mechanical properties and physical performance of the SAM technique.

HMGB1-C1q complexes regulate macrophage function by switching between leukotriene and specialized proresolving mediator biosynthesis.

Macrophage polarization is critical to inflammation and resolution of inflammation. We previously showed that high-mobility group box 1 (HMGB1) can engage receptor for advanced glycation end product (RAGE) to direct monocytes to a proinflammatory phenotype characterized by production of type 1 IFN and proinflammatory cytokines. In contrast, HMGB1 plus C1q form a tetramolecular complex cross-linking RAGE and LAIR-1 and directing monocytes to an antiinflammatory phenotype.

Mechanical sensitivity analysis and optimization of a large-aperture KDP frequency converter for higher SHG efficiency.

The effective energy density at the target of inertial confinement fusion facility is subject to the problem of the low efficiency of second harmonic generation of large-aperture KDP frequency converters over a long time. To overcome this problem, we propose the optomechanical analysis method to correlate the mechanical factors with its critical physical performance in theory. Further, combined with experiments and simulations, the mechanical sensitivity of the frequency converter is completely explained from the microscopic and macroscopic perspectives.

[Clinicopathological characteristics and prognosis analysis of colorectal synchronous multiple primary cancer].

Objective: To investigate the clinicopathological features and prognosis of colorectal synchronous multiple primary cancer(SMPC).

Methods: From January 2008 to June 2011, 51 patients diagnosed with colorectal SMPC underwent surgery at Department of General Surgery of Peking University First Hospital. Their clinicopathological features, diagnosis, treatment and prognosis were summarized and analyzed.

Water-Soluble Blue Fluorescence-Emitting Hyperbranched Polysiloxanes Simultaneously Containing Hydroxyl and Primary Amine Groups.

In this Communication, novel water-soluble hyperbranched polysiloxanes (WHPSs) simultaneously containing hydroxyl and primary amine groups are developed. The polymers are constructed via melt polycondensation, that is, transesterification reaction between ethoxyl groups of (3-aminopropyl)triethoxysilane and hydroxyl groups of dihydric alcohols, using a one-step process under catalyst-free conditions. Surprisingly, the resultant WHPSs can emit bright blue fluorescence in the 100% solid state under the irradiation of UV light, and their photoluminescence intensities in aqueous solutions continuously go up along with increasing concentrations.

Primary Retroperitoneal Seminoma Staging and Surveillance by Means of Fluoro-2-Deoxyglucose-Positron Emission Tomography/Computed Tomography.

Primary retroperitoneal seminoma is a very rare entity. We present a case of 39-year-old male with primary retroperitoneal seminoma with staging and surveillance by means of F-18 fluoro-2-deoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT). The case demonstrates that primary retroperitoneal seminoma can be easy to identify with FDG-PET/CT and potential follow-up on recurrence, or metastatic disease can be performed using this technique.

Focal Colonic FDG Activity with PET/CT: Guidelines for Recommendation of Colonoscopy.

Focal (18)F-fluorodeoxyglucose (FDG) colonic activity can be incidentally seen in positron emission tomography/computed tomography (PET/CT) scans. Its clinical significance is still unclear. The purpose of this study was to assess the significance of focal FDG activity in PET/CT scans by correlating the imaging findings to colonoscopy results, and come up with some guidelines for recommendation of follow-up colonoscopy.