Decoding the Atomic-Scale Structural Origin of Large Strain Performance in BNT-6BT Based Relaxor Ferroelectrics.

The relationship between matter properties and their atomic-scale structures is a challenging investigation. For relaxor ferroelectrics, correlating the relaxor mechanisms on the atomic scale to properties is still ambiguous. Here, the correlation between the atomic-scale structure and strain performance of 0.

AC/DC Electric-Field-Assisted Growth of ZnO Nanowires for Gas Discharge.

Using ZnO nanowires as needle anodes in gas discharge is helpful for maintaining continuous discharge with a relatively low voltage. It is necessary that the ZnO nanowires are far enough apart to guarantee no electric field weakening and that the nanowire anodes are easy to assemble together with the discharging devices. An AC/DC electric-field-assisted wet chemical method is proposed in this paper.

Single-cell individualized electroporation with real-time impedance monitoring using a microelectrode array chip.

The ability to precisely deliver molecules into single cells while maintaining good cell viability is of great importance to applications in therapeutics, diagnostics, and drug delivery as it is an advancement toward the promise of personalized medicine. This paper reports a single-cell individualized electroporation method with real-time impedance monitoring to improve cell perforation efficiency and cell viability using a microelectrode array chip. The microchip contains a plurality of sextupole-electrode units patterned in an array, which are used to perform in situ electroporation and real-time impedance monitoring on single cells.

Emerging Role of LncRNAs in Ischemic Stroke-Novel Insights into the Regulation of Inflammation.

As a crucial kind of pervasive gene, long noncoding RNAs (lncRNAs) are abundant and key players in brain function as well as numerous neurological disorders, especially ischemic stroke. The mechanisms underlying ischemic stroke include angiogenesis, autophagy, apoptosis, cell death, and neuroinflammation. Inflammation plays a vital role in the pathological process of ischemic stroke, and systemic inflammation affects the patient's prognosis.

Long-term and label-free monitoring for osteogenic differentiation of mesenchymal stem cells using force sensor and impedance measurement.

Stem cells have attracted increasing research interest in the field of regenerative medicine due to their unique abilities to differentiate into multiple cell lineages. Label-free, real-time, and long-term monitoring for stem cell differentiation is requisite in studying directional differentiation and development mechanisms for tissue engineering applications, but a great challenge because of the rigorous demands for sensitivity, stability and biocompatibility of devices. In this article, a label-free and real-time monitoring approach using a zinc oxide (ZnO) nanorod field effect transistor (FET) is proposed to detect cell traction forces (CTFs) exerted by cells on underlying substrates.

Microchip with Single-Cell Impedance Measurements for Monitoring Osteogenic Differentiation of Mesenchymal Stem Cells under Electrical Stimulation.

Effective induction methods and monitoring are essential for studying the mechanism of biological responses in stem cell differentiation. This article proposes an induction method incorporating electrical stimulation under an inhomogeneous field with single-cell impedance monitoring for studying osteogenic differentiation of mesenchymal stem cells (MSCs) using a microchip. The microchip contains an array of sextupole-electrode units for implementing a combination of controllable electrical stimulation and single-cell impedance measurements.

Retraction: Microelectrochemical cell arrays for whole-cell currents recording through ion channel proteins based on trans-electroporation approach.

Retraction of 'Microelectrochemical cell arrays for whole-cell currents recording through ion channel proteins based on trans-electroporation approach' by Tianyang Zheng et al., Analyst, 2020, 145, 197-205.

Correction: Microelectrochemical cell arrays for whole-cell currents recording through ion channel proteins based on trans-electroporation approach.

Correction for 'Microelectrochemical cell arrays for whole-cell currents recording through ion channel proteins based on trans-electroporation approach' by Tianyang Zheng, et al., Analyst, 2020, DOI: 10.1039/c9an01737b.

A microelectrode array chip for osteogenic differentiation of mesenchymal stem cells under electrical stimulation.

Electrical stimulation (ES) as an easy and effective inducing method has been widely used in induction differentiation of stem cells, e.g. osteogenic differentiation of mesenchymal stem cells (MSCs) for bone healing and bone tissue therapies.

Microelectrochemical cell arrays for whole-cell currents recording through ion channel proteins based on trans-electroporation approach.

High electrostability and long life-time of planar chip technology are crucial for electrophysiological measurements such as ionic current recording through ion channel proteins embedded in biological cell membrane. In this paper, we propose a novel planar microchip integrated with microelectrochemical cell array toward to a feasible solution for ion channel screening with high resolution and long life-time. In order to reduce the interference from the leakage currents, a synthetic lipid bilayer is applied to form a high sealing resistance.

Resveratrol Suppresses Epithelial-Mesenchymal Transition in GBM by Regulating Smad-Dependent Signaling.

Glioblastoma (GBM) is the most common and malignant intracranial tumor in adults. Despite continuous improvements in diagnosis and therapeutic method, the prognosis is still far away from expectations. The invasive phenotype of GBM is the main reason for the poor prognosis.

Flexible Trapping and Manipulation of Single Cells on a Chip by Modulating Phases and Amplitudes of Electrical Signals Applied onto Microelectrodes.

These days, multiplex assay with diverse functions on a single chip has become more and more imperative for biological cell research. Multipoint and multistep manipulation for single cells on a chip plays a significant role for cell characterization, immunoassays, and rare cell isolation, etc. In this article, a novel dielectrophoresis (DEP)-based manipulation method is proposed to flexibly move and position cells on a chip via applying various electrical signals onto microelectrodes.

Ginsenoside Rg1 attenuates protein aggregation and inflammatory response following cerebral ischemia and reperfusion injury.

Ginsenoside Rg1 (GS Rg1) is a glycosylated triterpenoid saponin extracted from Panax ginseng. We aim to investigate the impact of GS Rg1 on protein aggregation and inflammatory response in a cerebral ischemia/reperfusion (I/R) injury model. Rats were administered different doses of GS Rg1 (10, 20, or 40 mg/kg/day) or nimodipine (1 mg/kg/day) for 5 consecutive days.