Background: Malignant esophageal mediastinal fistula is a severe complication that occurs in both the advanced stages of esophageal cancer and after radiotherapy for esophageal cancer. Esophageal mediastinal fistula is very susceptible to complications such as mediastinitis and mediastinal abscess, resulting in a significantly elevated mortality rate for patients. We reported a rare case of esophageal mediastinal fistula after immunotherapy for non-small cell lung cancer (NSCLC).
View Article and Find Full Text PDFFront Med (Lausanne)
October 2024
Background: Icodextrin is a type of peritoneal dialysis (PD) osmolyte that can be extended retention times (8-16 h) and may offer a viable alternative to conventional glucose dialysis solutions for PD patients. Nonetheless, prolonged use of icodextrin may lead to allergic rash, and rarely severe skin lesions.
Case Presentation: In February 2024, a 45-year-old male was admitted to the Department of Nephrology at Shaoxing Second Hospital presenting with a 3-day history of intense generalized pruritic erythematous rash.
Rationale: Mycobacterium avium complex (MAC) infection is common in lung, liver and skin. However, MAC presenting with peritonitis is uncommon and is particularly rare in immunocompetent patients. We report a case of infection-associated glomerulonephritis and mantle cell lymphoma caused by peritonitis due to MAC.
View Article and Find Full Text PDFIntroduction: Acupuncture has been shown to be effective in restoring gastrointestinal function in tumor patients receiving the enhanced recovery after surgery (ERAS) protocol. The present systematic review and meta-analysis aimed to evaluate the rationality and efficacy of integrating acupuncture in the ERAS strategy to recuperate gastrointestinal function.
Methods: We searched eleven databases for relevant randomized clinical trials (RCTs) of acupuncture for the treatment of gastrointestinal dysfunction in tumor patients treated with the ERAS protocol.
Comb Chem High Throughput Screen
March 2023
Background: Radix Paeoniae Alba is a traditional Chinese herbal medicine. It can accelerate salivary secretion and alleviate the dry mouth of patients with Sjogren's syndrome (SS). Although it is widely used in clinical treatment, its target and mechanism remain unclear.
View Article and Find Full Text PDFComput Methods Programs Biomed
September 2022
Background And Objective: Computer tomography (CT) to cone-beam computed tomography (CBCT) image registration plays an important role in radiotherapy treatment placement, dose verification, and anatomic changes monitoring during radiotherapy. However, fast and accurate CT-to-CBCT image registration is still very challenging due to the intensity differences, the poor image quality of CBCT images, and inconsistent structure information.
Methods: To address these problems, a novel unsupervised network named cross-domain fusion registration network (CDFRegNet) is proposed.
Photodiagnosis Photodyn Ther
December 2021
Background: Indocyanine green fluorescence imaging technology has been widely used in liver resection. However, there has been a lack of strong evidence on whether application of indocyanine green fluorescence imaging enhances clinical outcomes in liver resection. This meta-analysis was performed to compare the latest clinical results of indocyanine green fluorescence imaging-guided hepatectomy (FIGH) and conventional hepatectomy (CH) in liver diseases.
View Article and Find Full Text PDFPurpose: Cone-beam computed tomography (CBCT) is a common on-treatment imaging widely used in image-guided radiotherapy. Fast and accurate registration between the on-treatment CBCT and planning CT is significant for and precise adaptive radiotherapy treatment (ART). However, existing CT-CBCT registration methods, which are mostly affine or time-consuming intensity- based deformation registration, still need further study due to the considerable CT-CBCT intensity discrepancy and the artifacts in low-quality CBCT images.
View Article and Find Full Text PDFPurpose: To investigate the effect of total glucoside of paeony (TGP) on gut microbiota in NOD mice with Sjögren's syndrome (SS), using high-throughput sequencing of 16SrRNA gene.
Methods: Twenty-four NOD mice were randomly assigned to 4 groups (n = 6 per group): sham group receiving deionized water (0.4 ml), hydroxychloroquin group receiving hydroxychloroquin (0.
IEEE Trans Biomed Eng
September 2020
Due to the complicated thoracic movements which contain both sliding motion occurring at lung surfaces and smooth motion within individual organs, respiratory estimation is still an intrinsically challenging task. In this paper, we propose a novel regularization term called locally adaptive total p-variation (LaTpV) and embed it into a parametric registration framework to accurately recover lung motion. LaTpV originates from a modified L-norm constraint (1 < p < 2), where a prior distribution of p modeled by the Dirac-shaped function is constructed to specifically assign different values to voxels.
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