Facilitative preparation of graphene/cellulose aerogels with tunable microwave absorption properties for ultra-lightweight applications.

Graphene aerogels, as a novel type of carbon-based composite material, have shown great potential in the field of wave absorption due to its characteristics of high conductivity, adjustable structure and good corrosion resistance. It is of great significance to precisely control the dielectric properties of graphene aerogel composites by effectively adjusting their microstructures through the preparing process design, ultimately leading to improve their wave-absorbing performances. In this study, two kinds of graphene/cellulose aerogel composites with three-dimensional porous structures, were successfully prepared using graphene and short staple cellulose as raw materials via the freeze-drying method based on the dissolution-regeneration strategy.

The TRIM21-FOXD1-BCL-2 axis underlies hyperglycaemic cell death and diabetic tissue damage.

Chronic hyperglycaemia is a devastating factor that causes diabetes-induced damage to the retina and kidney. However, the precise mechanism by which hyperglycaemia drives apoptotic cell death is incompletely known. Herein, we found that FOXD1, a FOX family transcription factor specifically expressed in the retina and kidney, regulated the transcription of BCL-2, a master regulator of cell survival.

A fast breeding strategy creates fragrance- and anthocyanin-enriched rice lines by marker-free gene-editing and hybridization.

Unlabelled: As rice is a staple food for nearly half of the world's population, rice varieties with excellent agronomic traits as well as high flavor and nutritional quality such as fragrant rice and purple rice are naturally favored by the market. In the current study, we adopt a fast breeding strategy to improve the aroma and anthocyanin content in the excellent rice inbred line, F25. The strategy skillfully used the advantages of obtaining editing pure lines in T0 generation of CRISPR/Cas9 editing system and easy observation of purple character and grain shape, integrated the subsequent screening of non-transgenic lines, and the elimination of undesirable edited variants from gene-editing and cross-breeding at the same time as the separation of the progeny from the purple cross, thus expediting the breeding process.

Rutin alleviates colon lesions and regulates gut microbiota in diabetic mice.

Diabetes is a common metabolic disorder that has become a major health problem worldwide. In this study, we investigated the role of rutin in attenuating diabetes and preventing diabetes-related colon lesions in mice potentially through regulation of gut microbiota. The rutin from tartary buckwheat as analyzed by HPLC was administered intragastrically to diabetic mice, and then the biochemical parameters, overall community structure and composition of gut microbiota in diabetic mice were assayed.

Novel Radiotracers for Molecular Imaging of Myocardial Inflammation: an Update Focused on Clinical Translation of Non-18F-FDG Radiotracers.

Purpose Of Review: The purpose of this paper is to provide a focused update on recent advances in non-18F-FDG radiotracers for myocardial inflammatory diseases, with a focus on cardiac sarcoidosis and myocarditis.

Recent Findings: Novel radiotracers targeting molecular features of inflammation have the potential to visualize underlying molecular mechanisms key to the pathogenesis of inflammatory cardiomyopathies such as sarcoidosis and myocarditis. These radiotracers may provide unique opportunities for improved mechanistic insight, higher specificity, and better quantification of disease activity, as well as potential for guidance and monitoring of immunomodulatory therapies.

Genome-Wide Analysis of MYB Transcription Factor Gene Superfamily Reveals BjPHL2a Involved in Modulating the Expression of in .

is an economically important vegetable and oilseed crop. The MYB transcription factor superfamily is one of the largest transcription factor families in plants, and plays crucial roles in regulating the expression of key genes involved in a variety of physiological processes. However, a systematic analysis of the MYB transcription factor genes in has not been performed.

Racial and Ethnic Disparities in All-Cause and Cardiovascular Mortality Among Cancer Patients in the U.S.

Background: With improved cancer survival, death from noncancer etiologies, especially cardiovascular disease (CVD) mortality, has come more into focus. Little is known about the racial and ethnic disparities in all-cause and CVD mortality among U.S.

Transcriptomic Analysis Revealed Key Defense Genes and Signaling Pathways Mediated by the Gene in Response to Infection with pv. Tomato DC3000.

Nucleocytoplasmic transport receptors play key roles in the nuclear translocation of disease resistance proteins, but the associated mechanisms remain unclear. The gene encodes an importin β-like protein. A transgenic Arabidopsis line overexpressing (OESAD2/Col-0) showed obvious resistance to pv.

Efficacy and Mechanism of Roxadustat plus Oral Iron in the Treatment of Elderly Chronic Kidney Disease with Anemia.

Objective: For investigating the efficacy and mechanism of Roxadustat + oral iron in the treatment of elderly chronic kidney disease (CKD) complicated with anemia.

Methods: A total of 100 elderly patients with CKD and anemia admitted to our hospital between April 2020 and December 2021 were enrolled as research subjects, and the patients were assigned to control group (Con group,  = 50) or experimental group (Exp group,  = 50). The patients in the Con group were given oral iron, and those in the Exp group were given Roxadustat capsule based on the Con group.

Rutin Promotes Pancreatic Cancer Cell Apoptosis by Upregulating miRNA-877-3p Expression.

(1) Background: pancreatic cancer is one of the most serious cancers due to its rapid and inevitable fatality, which has been proved very difficult to treat, compared with many other common cancers. Thus, developing an effective therapeutic strategy, especially searching for potential drugs, is the focus of current research. The exact mechanism of rutin in pancreatic cancer remains unknown.

Effect of Carbon on Dislocation Loops Formation during Self-Ion Irradiation in Fe-Cr Alloys at High Temperatures.

In this study, two types of ferritic model alloys (Fe-9Cr and Fe-9Cr-C) were simultaneously irradiated with 3.5 MeV Fe ions at 450 °C and 550 °C to a dose of 3dpa at the peak damage region, respectively. Transmission electron microscopy (TEM) was used to investigate the microstructural evolution of the Fe-Cr alloys after irradiation.

The Prognostic Value of Baseline Distant Metastasis in Icotinib-Treated Patients with -Mutated Stage IV Non-Small Cell Lung Cancer.

Purpose: Several studies have revealed the prognostic value distant metastasis in non-small-cell lung cancer (NSCLC) patients receiving first-line epidermal growth factor receptor (EGFR) inhibitors. However, the question of whether the specific metastatic site could predict survival outcomes remain elusive. This study evaluated the prognostic value of specific metastatic site at diagnosis in first-line icotinib-treated patients with -mutated advanced NSCLC.

Insurance disparity in cardiovascular mortality among non-elderly cancer survivors.

Background: Insurance status plays a vital role in cancer diagnosis, treatments and survival. Cancer patients have higher cardiovascular disease (CVD) mortality than the general population.

Methods: The Surveillance, Epidemiology and End Results (SEER) program 2007-2016 was used to estimate the CVD mortality among cancer patients aged 18 to 64 years at the time of diagnosis of an initial malignancy with the eight most prevalent cancers.

Patients With Acute Ischemic Stroke Who Receive Brain Magnetic Resonance Imaging Demonstrate Favorable In-Hospital Outcomes.

Background Use of inpatient brain magnetic resonance imaging (MRI) in patients with acute ischemic stroke is highly institution dependent and has been associated with increased length and cost of hospital stay. We examined whether inpatient brain MRI in patients with acute ischemic stroke is associated with improved clinical outcomes to justify its resource requirements. Methods and Results The National Inpatient Sample database was queried retrospectively to find 94 003 patients who were admitted for acute ischemic stroke and then received inpatient brain MRI between 2012 and 2014.

Hemodynamic monitoring in patients with venoarterial extracorporeal membrane oxygenation.

Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is an effective mechanical circulatory support modality that rapidly restores systemic perfusion for circulatory failure in patients. Given the huge increase in VA-ECMO use, its optimal management depends on continuous and discrete hemodynamic monitoring. This article provides an overview of VA-ECMO pathophysiology, and the current state of the art in hemodynamic monitoring in patients with VA-ECMO.

Laser with 10 short-term instability for compact optically pumped cesium beam atomic clock.

We realize a high-stability laser by modulation transfer spectroscopy and apply it to implement a high-performance compact optically pumped cesium beam atomic clock. Evaluated by the optical heterodyne method with two identical frequency-stabilized lasers, the frequency instability of the 852 nm laser directly referenced on thermal atoms is 2.6×10 at the averaging time of 5 s.

Effects of Silicon Content and Tempering Temperature on the Microstructural Evolution and Mechanical Properties of HT-9 Steels.

Two kinds of experimental ferritic/martensitic steels (HT-9) with different Si contents were designed for the fourth-generation advanced nuclear reactor cladding material. The effects of Si content and tempering temperature on microstructural evolution and mechanical properties of these HT-9 steel were studied. The microstructure of experimental steels after quenching and tempering were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), and transmission electron microscopy (TEM); the mechanical properties were investigated by means of tensile test, Charpy impact test, and hardness test.

High-resolution performance of triptycene functionalized with polycaprolactones for gas chromatography.

Developing highly selective stationary phases is essential to address the issues for separation of analytes with similar properties and various components in complex samples. Herein, we report a new triptycene-based material functionalized with polycaprolactone moieties (TP-PCL) as the stationary phase with high-resolution performance for gas chromatography (GC). The TP-PCL capillary column exhibited column efficiency of 5555 plates/m and moderate polarity.

The nuclear transporter SAD2 plays a role in calcium- and H O -mediated cell death in Arabidopsis.

In response to pathogens, plant cells exhibit a rapid increase in the intracellular calcium concentration and a burst of reactive oxygen species (ROS). The cytosolic increase in Ca and the accumulation of ROS are critical for inducing programmed cell death (PCD), but the molecular mechanism is not fully understood. We screened an Arabidopsis mutant, sad2-5, which harbours a T-DNA insertion in the 18 exon of the importin beta-like gene, SAD2.

Realization of phase locking in good-bad-cavity active optical clock.

The residual cavity-pulling effect limits further narrowing of linewidth in dual-wavelength (DW) good-bad-cavity active optical clocks (AOCs). In this paper, we for the first time experimentally realize the cavity-length stabilization of the 1064/1470 nm DW-AOCs by utilizing the phase locking technique of two independent 1064 nm good-cavity lasers. The frequency tracking accuracy between the two main-cavities of DW-AOCs is better than 3 × 10 at 1 s, and can reach 1 × 10 at 1000 s.

Molecular Detection of Eukaryotic Diets and Gut Mycobiomes in Two Marine Sediment-Dwelling Worms, Sipunculus nudus and Urechis unicinctus.

The present study aimed to reveal the eukaryotic diets of two economically important marine sediment-inhabiting worms, Sipunculus nudus (peanut worm) and Urechis unicinctus (spoon worm), using clone libraries and phylogenetic analyses of 18S rRNA genes. Fungal rDNA was also targeted and analyzed to reveal mycobiomes. Overall, we detected a wide range of eukaryotic phylotypes associated with the larvae of S.

Dual-Wavelength Good-Bad-Cavity Laser System for Cavity-Stabilized Active Optical Clock.

Active optical clocks (AOCs) have the intrinsic suppression of the influence of the cavity's noise on the output frequency, giving rise to the potentially ultranarrow linewidth. To break the cavity's thermal noise limitation by taking full advantage of the AOC's principle, as well as to achieve a long-term instability, we propose a scheme of cavity-stabilized active optical clock. The system consists of two key procedures.