Publications by authors named "Tianmeng Shao"
Article Synopsis
- Psoriatic arthritis (PsA) is a type of arthritis that causes inflammation and can damage bones. Researchers found more special cells (called CD16-positive monocytes) in people with PsA.
- They tested these cells in the lab to see how they could turn into bone-destroying cells (osteoclasts) and learned that certain chemicals promote this change.
- The study showed that a higher number of these CD16-positive cells is linked to more bone damage in PsA, suggesting that CD16 might help identify these cells in people with inflammatory arthritis.
Psoriatic arthritis (PsA) is a chronic and erosive form of arthritis of unknown cause. We aimed to characterize the PsA phenotype using gene expression profiling and comparing it with healthy control subjects and patients rheumatoid arthritis (RA). Peripheral blood cells (PBCs) of 19 patients with active PsA and 19 age- and sex-matched control subjects were used in the analyses of PsA, with blood samples collected in PaxGene tubes.
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