The Expression Regulatory Network in the Lung Tissue of Tibetan Pigs Provides Insight Into Hypoxia-Sensitive Pathways in High-Altitude Hypoxia.

To adapt to a low-oxygen environment, Tibetan pigs have developed a series of unique characteristics and can transport oxygen more effectively; however, the regulation of the associated processes in high-altitude animals remains elusive. We performed mRNA-seq and miRNA-seq, and we constructed coexpression regulatory networks of the lung tissues of Tibetan and Landrace pigs. 2, and 1 were identified as major regulators of hypoxia-induced genes that regulate blood pressure and circulation, and they were enriched in pathways related to signal transduction and angiogenesis, such as -1, 3-, and .

Vascular characteristics and expression of hypoxia genes in Tibetan pigs' hearts.

Background: Tibetan pigs have exhibited unique characteristics from low-altitudes pigs and adapted well to the Qinghai-Tibet Plateau.

Objectives: The current study was undertaken to investigate the hypoxic adaptation of heart in Tibetan pigs.

Methods: The hearts of Tibetan pigs and Landrace pigs raised at high or low altitudes were compared using 3D casting technology, scanning electron microscopy and real-time quantitative PCR (qRT-PCR).

Characteristics of Tibetan pig lung tissue in response to a hypoxic environment on the Qinghai-Tibet Plateau.

To adapt to the plateau environment, Tibetan pigs' lungs have developed a unique physiological mechanism during evolution. The vascular corrosion casting technique and scanning electron microscopy were used to understand arterial architecture. Blood physiological index and quantitative real-time PCR (qRT-PCR) were used for assessing whether the lung can regulate the body through anatomical, physiological and molecular mechanisms to adapt to hypoxic environments.

Laboratory experiments on HMC coupling mechanisms in innovative clean foundation treatments for Zn-contaminated dredger fills.

Large-scale contaminated dredger fills have comprehensively resulted from human activities and geological deposition processes, and their disposal is a worldwide challenge. Innovative soil remediation coupling foundation treatment methods, namely, clean foundation treatment methods (CFTMs), were proposed and verified using a hydraulic-mechanical-chemical coupling triaxial testing system. The CFTM exploration triaxial tests on undisturbed clayey, silty, and sandy dredger fills showed that the critical injection significantly dilated soil volume even after the soil was vacuum pumped.

Distribution and origination of zinc contamination in newly reclaimed heterogeneous dredger fills: Field investigation and numerical simulation.

Heavy metal elements, including Zn, Cd, As, Ni, Cu, Pb and Cr, were detected in soils (no deeper than 75 m) from newly reclaimed zones of Shanghai, China. The Zn concentration exceeded soil quality limits. The Zn contamination was tested in both dredger fills and sedimentary layers (①, ②, ④ and ⑤).

Three-Dimensional Numerical Investigation of Pore Water Pressure and Deformation of Pumped Aquifer Systems.

Excessive groundwater withdrawal has caused severe land subsidence worldwide. The pore water pressure and the deformation of pumped hydrostratigraphic units are complex. A fully coupled three-dimensional numerical simulation was carried out for different pumping plans in this paper.

Health Diagnosis of Major Transportation Infrastructures in Shanghai Metropolis Using High-Resolution Persistent Scatterer Interferometry.

Since the Persistent Scatterer Synthetic Aperture Radar (SAR) Interferometry (PSI) technology allows the detection of ground subsidence with millimeter accuracy, it is becoming one of the most powerful and economical means for health diagnosis of major transportation infrastructures. However, structures of different types may suffer from various levels of localized subsidence due to the different structural characteristics and subsidence mechanisms. Moreover, in the complex urban scenery, some segments of these infrastructures may be sheltered by surrounding buildings in SAR images, obscuring the desirable signals.

Functional neuroimaging of extraversion-introversion.

Neuroimaging techniques such as functional magnetic resonance imaging and positron emission tomography have provided an unprecedented neurobiological perspective for research on personality traits. Evidence from task-related neuroimaging has shown that extraversion is associated with activations in regions of the anterior cingulate cortex, dorsolateral prefrontal cortex, middle temporal gyrus and the amygdala. Currently, resting-state neuroimaging is being widely used in cognitive neuroscience.

Decreased inhibitory control of negative information in directed forgetting.

A great deal of evidence suggests that emotion enhances memory. Thus, it may be harder to forget emotional information. By means of fMRI, this question was investigated in the item-method directed forgetting paradigm.

Changes of Functional Brain Networks in Major Depressive Disorder: A Graph Theoretical Analysis of Resting-State fMRI.

Recent developments in graph theory have heightened the need for investigating the disruptions in the topological structure of functional brain network in major depressive disorder (MDD). In this study, we employed resting-state functional magnetic resonance imaging (fMRI) and graph theory to examine the whole-brain functional networks among 42 MDD patients and 42 healthy controls. Our results showed that compared with healthy controls, MDD patients showed higher local efficiency and modularity.

[Study on ingredients of essential oils of Curcuma wenyujin extracted by supercritical-CO2 fluid extraction and steam distillation].

Objective: To compare the ingredients of essential oils of Curcuma wenyujin extracted by supercritical-CO2 fluid extraction and by steam distillation.

Method: GC-MS was applied in this experiment.

Result: The ingredients and physical and chemical properties of essential oils of C.