The Novel Target of Colorectal Carcinoma: TRIM44 Regulates Cell Migration and Invasion via Activation of CXCR4/NF-κB Signaling.

Tripartite motif containing 44 (TRIM44) has been reported to regulate various biological effects in malignant cancers and matrix Metalloproteinases has been demonstrated to be associated with cancer cell migration and invasion. Nonetheless, the expression and molecular mechanism of TRIM44 in colorectal cancer (CRC) remain rarely known. TRIM44 was overexpressed or knocked down in CRC cells.

A rare and rapidly progressing renal chondrosarcoma: a case report.

Mesenchymal chondrosarcoma of the kidney is a rare soft tissue sarcoma. We report a 64-year-old female with a right renal pelvic mass. After a right nephrectomy was performed, the histopathological examination confirmed the diagnosis to be primary extraskeletal mesenchymal chondrosarcoma.

HPT axis‑independent TSHβ splice variant regulates the synthesis of thyroid hormone in mice.

Thyroid stimulating hormone (TSH) consists of an α‑subunit and a unique β‑subunit. The first in‑frame TSHβ splice variant produced by the cells of immune system was identified in 2009. The TSHβ splice variant and native TSHβ exhibit different expression profiles, and research has been conducted to elucidate the role of the TSHβ splice variant in different diseases.