Relationships between jaw deformity and the occlusal plane in cone beam computed tomography scans.

Statement Of Problem: Consistent findings about the relationships between jaw deformity and the occlusal plane are lacking.

Purpose: The purpose of this clinical study was to explore the relationships between the occlusal plane and jaw deformity by measuring data obtained from cone beam computed tomography (CBCT) scans.

Material And Methods: Reconstructed images simulated by using the Materialise Interactive Medical Image Control System (Mimics) software program of CBCT data of 80 participants with facial asymmetry and 42 participants from the normal control group were measured with a new 3-dimensional geometric morphologic measurement system.

Deletion of hephaestin and ceruloplasmin induces a serious systemic iron deficiency and disrupts iron homeostasis.

Multi-copper ferroxidases (MCFs) play important roles in cellular iron metabolism and homeostasis. In this study, we generated the hephaestin (Heph), ceruloplasmin (Cp) single and Heph/Cp double knockout (KO) mice to investigate the roles of MCFs in iron transport among system and vital organs in mice at 4 weeks and 6 months of age. Compared with wild-type (WT) mice, Heph/Cp mice at both ages presented with severe anemia and significantly lower iron level in the serum and spleen, but with significantly higher iron level in the liver, heart, kidney, and duodenal enterocytes.