Aeromonas veronii-associated bacteremia in the course of treatment of acute myeloid leukemia: a case report and review of the literature.

Purpose: This study aimed to report a case of acute myeloid leukemia (AML) complicated by Aeromonas veronii infection-induced bacteremia and to review relevant literature on the etiology, prevention, treatment, and prognosis of bacteremia in immunocompromised populations, aiming to reduce mortality in individuals with hematologic and other end-stage diseases and improve patient outcomes.

Methods And Results: We reported the case of a 23-year-old male patient with relapsed AML characterized by AML1:ETO and ASXL positivity, classified as a high-risk group. The patient presented with fever, abdominal pain, diarrhea, nausea, and vomiting after consuming partially cooked fish.

Ultra-sensitive pressure sensor with low-temperature crosstalk based on the Vernier effect and helical structure.

What we believe to be a novel high-sensitivity fiber-optic pressure sensor based on the vernier effect and helical structure is proposed and experimentally verified. The sensor utilizes the superposition of higher-order mode Mach-Zehnder interference and Sagnac fundamental mode polarization interference in a single fiber ring to achieve the vernier effect. In addition, a non-invasive encapsulation structure was fabricated to convert the rise and fall of the pressure value into the change in the twist angle of the optical fiber.

Correlation between 24-Hour Ambulatory Blood Pressure Variability and White Matter Lesions in Patients with Cerebral Small Vascular Disease: A Cross-Sectional Study.

Objective: The goals of this study are to assess the correlation between 24-hour ambulatory blood pressure (BP) variability and white matter lesions (WML) in patients with cerebral small vascular disease (CSVD) and to provide guidance for the prevention of WML.

Methods: A total of 136 patients diagnosed with CSVD and essential hypertension were recruited and divided into two groups. The Fazekas scale was used to quantify the severity of WML.

Exosomal miRNA-223-3p as potential biomarkers in patients with cerebral small vessel disease cognitive impairment.

Background: Cerebrovascular disease is a common clinical illness. Many patients with cerebrovascular disease can be accompanied by cognitive impairment. The exosomal microRNA (miRNA)-223-3p is related to vascular endothelial injury, synaptic function, inflammatory response, and other mechanisms.

αMSH prevents ROS-induced apoptosis by inhibiting Foxo1/mTORC2 in mice adipose tissue.

Alpha-melanocyte stimulating hormone (αMSH) is an important adenohypophysis polypeptide hormone that regulates body metabolic status. To date, it is well known that the disorder of hypothalamic αMSH secretion is related to many metabolic diseases, such as obesity and type II diabetes. However, the underlying mechanisms are poorly understood.

Adiponectin reduces ER stress-induced apoptosis through PPARα transcriptional regulation of ATF2 in mouse adipose.

Adiponectin is a cytokine produced predominantly by adipose tissue and correlates with glucose and lipid homeostasis. However, the effects of adiponectin on endoplasmic reticulum (ER) stress and apoptosis of adipose tissue remain elusive. In this study, we found that tunicamycin-induced ER stress increased serum free fatty acid (FFA) and impaired glucose tolerance, elevated the mRNA levels of GRP78, Chop, ATF2 and caspase 3, but reduced adiponectin mRNA level in white adipose tissue.

αMSH promotes preadipocyte proliferation by alleviating ER stress-induced leptin resistance and by activating Notch1 signal in mice.

Alpha-melanocyte stimulating hormone (αMSH) has an important role in the regulation of body weight and energy expenditure. Nevertheless, the molecular mechanisms of circulating αMSH on preadipocyte proliferation remain elusive. We found αMSH was reduced by high fat diet (HFD) while leptin was elevated in adipose tissue.

Sirt1 decreased adipose inflammation by interacting with Akt2 and inhibiting mTOR/S6K1 pathway in mice.

Sirtuin type 1 (Sirt1) and protein kinase B (Akt2) are associated with development of obesity and inflammation, but the molecular mechanisms of Sirt1 and Akt2 interaction on adipose inflammation remain unclear. To explore these mechanisms, a mouse model was used. Mice were fed with a high-fat diet (HFD) for 8 weeks, with interventions of resveratrol (RES) or nicotinamide (NAM) during the last 15 days.

Laser oscillation of Yb³⁺:Er³⁺ co-doped phosphosilicate microsphere [invited].

A fiber-taper-microsphere-coupled system was used to research the characteristics of laser oscillation and upconversion luminescence of Yb3+:Er3+ co-doped phosphosilicate (YECP) microspheres. The YECP microspheres were fabricated by melting the end of phosphosilicate filaments. Single- and multimode laser oscillation at 1535-1565 nm within the C-band were obtained.

Effects of molecular sieving and electrostatic enhancement in the adsorption of organic compounds on the zeolitic imidazolate framework ZIF-8.

In this work, the adsorption behavior of a range of organic vapors and gases on the zeolitic imidazolate framework, ZIF-8, is investigated using an inverse gas chromatography (IGC) methodology at the zero-coverage limit and elevated temperatures. The measured thermodynamic values and surface energies for the adsorption of n-alkanes on ZIF-8 are found to be reduced from those previously reported for IRMOF-1. This reduction is most likely an effect of the predominately organic accessible surface of ZIF-8 and the resulting weaker interactions in comparison to IRMOF-1.

Enhancing the stability of metal-organic frameworks in humid air by incorporating water repellent functional groups.

We report a modular construction of a new metal-organic framework (MOF) by strategically incorporating a number of water repellent functional groups in the frameworks. These MOFs demonstrate both open structure for high sorption capability and strong water resistance.

Trends in the adsorption of volatile organic compounds in a large-pore metal-organic framework, IRMOF-1.

Metal-organic frameworks have been proposed as useful sorbents for the capture of a variety of compounds. In this work, inverse gas chromatography (IGC) utilizing micropacked capillary columns was used to probe the adsorption of more than 30 volatile organic compounds (VOCs) on IRMOF-1. In an attempt to study the effect of structural degradation upon VOC adsorption, multiple samples of IRMOF-1 with widely ranging properties were investigated.

Resonant Raman spectroscopy of individual strained single-wall carbon nanotubes.

Resonance Raman spectra of individual strained ultralong single-wall carbon nanotubes (SWNTs) are studied. Torsional and uniaxial strains are introduced by atomic force microscopy manipulation. Torsional strain strongly affects the Raman spectra, inducing a large downshift in the E2 symmetry mode in the G+ band, but a slight upshift for the rest of the G modes and also an upshift in the radial breathing mode (RBM).

Raman spectral probing of electronic transition energy Eii variation of individual SWNTs under torsional strain.

We present herein a rational approach to probe the torsional strain-induced electronic transition energy Eii variation of individual SWNTs by resonant Raman spectroscopy (RRS). When a SWNT was manipulated by AFM tip through a path perpendicular to SWNT axis, both torsional and uniaxial strain would be introduced in SWNTs. Under the torsional strain, resonant Raman spectral mapping along a SWNT detected an M-shaped frequency (omegaRBM) and W-shaped intensity (IS) variation of radial breathing mode (RBM) spectra, which were induced by the elastic retraction of the nanotubes in combination with the friction after the tip has been removed.