Publications by authors named "Tianji Luan"
Article Synopsis
- - This research investigates how mutations in the phosphatase and tensin homolog (PTEN) gene affect liver cancer (HCC), specifically focusing on the loss of its tumor-suppressing functions.
- - Using bioinformatics and databases, the study found a high mutation frequency of the R130Q/G/L sites on the PTEN gene and utilized CRISPR-Cas12a to confirm the R130Q mutation in clinical HCC samples.
- - The findings suggest that CRISPR-Cas12a could be a valuable clinical tool for screening and prognostic assessment of HCC by detecting PTEN mutations.
Undifferentiated embryonic sarcoma of the adult liver with paraneoplastic syndrome: a case report.
Transl Cancer Res
December 2022
Background: Undifferentiated embryonic sarcoma of the liver (UESL) is a rare primary liver sarcoma that mainly affects children. Since it was first reported in 1978, less than 100 cases of UESL in adults have been reported. Due to the lack of specificity of clinical symptoms and imaging findings, the misdiagnosis rate of UESL is very high, and the definite diagnosis is usually in the late stage.
View Article and Find Full Text PDFThyroid cancer is a great part of the endocrine tumor with an increasing incidence. Papillary thyroid carcinoma (PTC) is the most common subtype. With the enormous pace taken in the microarray technology, bioinformatics is applied in data mining more frequently.
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