Cancer cachexia reduces the efficacy of immune checkpoint inhibitors in cancer patients.

Objective: Cachexia, a multifactorial syndrome, is frequently noticed in cancer patients. A recent study has shown inconsistent findings about the relationship between cachexia and the efficiency of immune checkpoint inhibitors (ICIs). To analyze this disparity, we did a meta-analysis.

Trust, discrimination and preference for shared decision-making in adolescents diagnosed with depression: Implications from Chinese mental health professionals.

Background: While evidence suggests that the attitudes of healthcare providers toward medical decision-making in adolescents diagnosed with depression merit exploration, research on their preferences for Shared Decision-Making (SDM) and the factors affecting these preferences remains limited.

Objective: To investigate Chinese mental health professionals' (MHPs) preferences for SDM in adolescents with depression and identify the relationships between their preference for SDM and trust and discrimination.

Methods: A cross-sectional design was used in this study.

Genome-Wide Identification of DOF Gene Family and the Mechanism Dissection of Regulating Starch Biosynthesis in Sorghum.

Starch is one of the main utilization products of sorghum ( L.), the fifth largest cereal crop in the world. Up to now, the regulation mechanism of starch biosynthesis is rarely documented in sorghum.

Profiling of transcriptional regulators associated with starch biosynthesis in sorghum ( L.).

Starch presents as the major component of grain endosperm of sorghum ( L.) and other cereals, serving as the main energy supplier for both plants and animals, as well as important industrial raw materials of human beings, and was intensively concerned world widely. However, few documents focused on the pathway and transcriptional regulations of starch biosynthesis in sorghum.

A Novel Approach of Feature Space Reconstruction with Three-Way Decisions for Long-Tailed Text Classification.

Text classification is widely studied by researchers in the natural language processing field. However, real-world text data often follow a long-tailed distribution as the frequency of each class is typically different. The performance of current mainstream learning algorithms in text classification suffers when the training data are highly imbalanced.

Effect of different irrigation levels on quality parameters of 'Honeycrisp' apples.

Background: Water shortage is the main factor affecting agricultural production in the vast arid and semi-arid areas of northern China. Using proper irrigation methods can optimize the efficiency of water use and improve the quality of agricultural products. This study investigated the effect of different irrigation levels on the quality of 'Honeycrisp' apples grown in the Loess Plateau of northern China.

The Prevalence and Determinant of PTSD Symptoms among Home-Quarantined Chinese University Students during the COVID-19 Pandemic.

Background: When COVID-19 emerged in China in late 2019, most Chinese university students were home-quarantined to prevent the spread of the virus, considering the great impact of the lockdown on young people habits and their psychological well-being. This study explored the prevalence of post-traumatic stress disorder (PTSD) and its associated factors among Chinese university students who are isolated at home during the COVID-19 pandemic.

Method: 4520 participants from five universities in China were surveyed by online questionnaire and the PTSD Checklist-Civilian Version (PCL-C) was adopted as a screening instrument.

Patients with mild and general COVID-19 should be negative for at least 3 consecutive nucleic acid tests before discharged.

Given the global spread of coronavirus disease (COVID-19), strict discharge standard is of great significance for the prevention and control of the epidemic, thus, the purpose of this study is to formulate more strict and scientific discharge standards. A total of 845 patients with mild and general COVID-19 who were considered to be discharged from hospital were included in this study. The median time from the onset of COVID-19 to the occurrence of two consecutive negative nucleic acid tests of these patients was 21 days.

Factors Associated with Mental Health Results among Workers with Income Losses Exposed to COVID-19 in China.

The outbreak and worldwide spread of COVID-19 has resulted in a high prevalence of mental health problems in China and other countries. This was a cross-sectional study conducted using an online survey and face-to-face interviews to assess mental health problems and the associated factors among Chinese citizens with income losses exposed to COVID-19. The degrees of the depression, anxiety, insomnia, and distress symptoms of our participants were assessed using the Chinese versions of the Patient Health Questionnaire-9 (PHQ-9), the Generalized Anxiety Disorder-7 (GAD-7), the Insomnia Severity Index-7 (ISI-7), and the revised 7-item Impact of Event Scale (IES-7) scales, respectively, which found that the prevalence rates of depression, anxiety, insomnia, and distress caused by COVID-19 were 45.

Initial measurement of electron nonextensive parameter with electric probe.

Theoretical analysis and a large number of experiments have proved that plasma components do not satisfy Boltzmann-Gibbs statistics and can be well described by nonextensive statistical mechanics, while new plasma parameters, electron nonextensive parameters, which are introduced to describe the nonextensive properties of plasma, cannot be diagnosed yet. Here we show measurement of electron nonextensive parameters of plasma with a nonextensive single electric probe. Our results show that nonextensive electric probe may play a role in plasma diagnosis, measuring nonextensivity of plasma and improving diagnostic accuracy of other plasma parameters.

[Effect of prokinetic agents on the electrical activity of stomach and duodenum in rats].

Objective: To determine the effect of prokinetic agents such as domperidone, mosapride, clarithromycin, and itopride on the electrical activity of the stomach and duodenum in SD rats,and also to explore the mechanism.

Methods: The organism functional experiment system BL-420E was used to record the myoelectrical activity in the stomach and duodenum of SD rats in all groups using domperidone, mosapride, itopride, clarithromycin, and physiological saline on the interdigestive phase. The effect of the prokinetic agents on the amplitude and frequency of gastric and duodenal electromyogram in the SD rats was compared.

Preparative separation and purification of deoxyschisandrin and gamma-schisandrin from Schisandra chinensis (Turcz.) Baill by high-speed counter-current chromatography.

High-speed counter-current chromatography (HSCCC) was successfully applied to the preparative separation and purification of deoxyschisandrin and gamma-schisandrin from the crude petroleum ether extracts of Schisandra chinensis (Turcz.) Baill. The optimum solvent system composed of n-hexane-methanol-water (35:30:3, v/v) led to the successful preparation of deoxyschisandrin and gamma-schisandrin.