Major depressive disorder (MDD) is one of the biggest threats to human mental health. MDD is characterized by aberrant changes in both structure and function of the brain. Although recent studies have developed some deep learning models based on multi-modal magnetic resonance imaging (MRI) for MDD diagnosis, the latent associations between deep features derived from different modalities were largely unexplored by previous studies, which we hypothesized may have potential benefits in improving the diagnostic accuracy of MDD.
View Article and Find Full Text PDFThe mammalian cerebral cortex is characterized by a 6-layer structure, and proper neuronal migration is critical for its formation. Cyclin-dependent kinase 5 (Cdk5) has been shown to be a critical kinase for neuronal migration. Several Cdk5 substrates have been suggested to be involved in ordered neuronal migration.
View Article and Find Full Text PDFPurpose: Enhanced Recovery after Surgery has been proven effective for patients with gastrointestinal cancer. But radical enhanced recovery could also lead to adverse clinical outcomes. Compared with reports on the estimation of successful implementation of enhanced recovery, studies on risk factors of enhanced recovery failure are still lacking.
View Article and Find Full Text PDFCarbon nanotube (CNT) thin-film transistors are expected to be promising for use in flexible electronics including flexible and transparent integrated circuits and in wearable chemical and physical sensors and for driving the circuits of flexible display panels. However, current devices based on CNT channels suffer from poor performance uniformity and low manufacturing yield; therefore, they are still far from being practical. This is usually caused by nonuniform deposition of the semiconducting CNTs and the rough surface of flexible substrates.
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