Publications by authors named "Tiandan Yang"
Article Synopsis
- Acute respiratory infections (ARIs) are a major health concern among children, with over 68% of hospitalized cases linked to respiratory pathogens in eastern Guangdong, China, from May 2019 to July 2023.
- The study found that Cytomegalovirus, Streptococcus pneumoniae, and Respiratory Syncytial Virus were the most common pathogens, with viral infections predominating, particularly in younger patients, and showing a peak at six months.
- Meteorological factors like air quality and temperature significantly impacted infection rates, suggesting the importance of monitoring these conditions to better understand and manage ARI hospitalizations in pediatric care.
RT-RPA-Ago detection platform for one-tube simultaneous typing diagnosis of human respiratory syncytial virus.
Front Cell Infect Microbiol
August 2024
Human respiratory syncytial virus (HRSV) is the most prevalent pathogen contributing to acute respiratory tract infections (ARTI) in infants and young children and can lead to significant financial and medical costs. Here, we developed a simultaneous, dual-gene and ultrasensitive detection system for typing HRSV within 60 minutes that needs only minimum laboratory support. Briefly, multiplex integrating reverse transcription-recombinase polymerase amplification (RT-RPA) was performed with viral RNA extracted from nasopharyngeal swabs as a template for the amplification of the specific regions of subtypes A (HRSV) and B (HRSV) of HRSV.
View Article and Find Full Text PDFAntimicrobial resistance (AMR) has posed a global threat to public health. The Staphylococcus aureus strains have especially developed AMR to practically all antimicrobial medications. There is an unmet need for rapid and accurate detection of the S.
View Article and Find Full Text PDFObjective: To explore the efficacy and safety of high-frequency oscillatory ventilation (HFOV) in the treatment of severe meconium aspiration syndrome (MAS) complicated with severe acute respiratory distress syndrome (ARDS).
Methods: A total of 65 infants with severe MAS complicated with severe ARDS were included in the study. The clinical efficacy of treatment for the HFOV group (n = 31) and the conventional mechanical ventilation (CMV) group (n = 34) was retrospectively analysed.