Vancomycin-Loaded Sol-Gel System for In Situ Coating of Artificial Bone to Prevent Surgical Site Infections.

Surgical site infections (SSIs) related to implants have always been a major challenge for clinical doctors and patients. Clinically, doctors may directly apply antibiotics into the wound to prevent SSIs. However, this strategy is strongly associated with experience of doctors on the amount and the location of antibiotics.

Evaluation of standard breast ultrasonography by adding two-dimensional and three-dimensional shear wave elastography: a prospective, multicenter trial.

Objective: To reduce the number of biopsies performed on benign breast lesions categorized as BI-RADS 4-5, we investigated the diagnostic performance of combined two-dimensional and three-dimensional shear wave elastography (2D + 3D SWE) with standard breast ultrasonography (US) for the BI-RADS assessment of breast lesions.

Methods: A total of 897 breast lesions, categorized as BI-RADS 3-5, were subjected to standard breast US and supplemented by 2D SWE only and 2D + 3D SWE analysis. Based on the malignancy rate of less than 2% for BI-RADS 3, lesions assessed by standard breast US were reclassified with SWE assessment.

Head-to-head comparison of perfluorobutane contrast-enhanced US and multiparametric MRI for breast cancer: a prospective, multicenter study.

Background: Multiparametric magnetic resonance imaging (MP-MRI) has high sensitivity for diagnosing breast cancers but cannot always be used as a routine diagnostic tool. The present study aimed to evaluate whether the diagnostic performance of perfluorobutane (PFB) contrast-enhanced ultrasound (CEUS) is similar to that of MP-MRI in breast cancer and whether combining the two methods would enhance diagnostic efficiency.

Patients And Methods: This was a head-to-head, prospective, multicenter study.

Pyroptosis-Related Gene Signature and Expression Patterns in the Deterioration of Atherosclerosis.

Background: Pyroptosis has been shown to be involved in the overall process of atherosclerosis. This study was aimed at investigating pyroptosis-related gene expression patterns in atherosclerosis and their diagnostic significance.

Methods And Results: In GSE100927, fifty-four pyroptosis-related genes were identified.

Synergistic removal of As(V) from aqueous solution by nanozero valent iron loaded with zeolite 5A synthesized from fly ash.

Nanozero valent iron (NZVI) loaded on zeolite 5A can efficiently remove As(V) in water through the synergism of zeolite 5A and NZVI. In this study, zeolite 5A was first obtained by ion exchange using zeolite 4A synthesized from fly ash and CaCl, and then NZVI-5A zeolite was synthesized by a reduction method to load NZVI on zeolite 5 A. NZVI-5A zeolite had a specific surface area of 238 m/g.

Immobilization persistence of Cu, Cr, Pb, Zn ions by the addition of steel slag in acidic contaminated mine soil.

Adding steel slag to the acidic contaminated mine soil can immobilize heavy metal ions, but immobilization persistence of the metal ions needs to be determined. In this study, dynamic column simulation experiments were set up to compare the immobilization persistence of Cu, Cr, Pb and Zn ions in original soil and with the addition of slag, lime or fly ash to the soil during a simulated 36-month of acid rain leaching. After adding slag and lime, the pH, organic matter content and cation exchange capacity of soil were significantly increased.

Quantitative shear wave elastography in primary invasive breast cancers, based on collagen-S100A4 pathology, indicates axillary lymph node metastasis.

Background: The purpose of this study was to evaluate the value of quantitative shear wave elastography (SWE) in indicating the axillary lymph node metastasis (LNM) of invasive breast cancers (IBCs) and to investigate if S100A4 plays a key role in promoting metastasis and increasing stiffness in IBC.

Methods: The differences in SWE of 223 IBC patients were compared between the LNM+ and LNM- groups and the optimal cutoff values of SWE for diagnosing LNM were calculated. We searched the gene expression omnibus (GEO) to determine whether S100A4 was more highly expressed in IBCs that were LNM+ than in those that were LNM-.