Clinical study of different frequency transcranial magnetic stimulation combined with paroxetine in the treatment of poststroke depression with insomnia.

Background: Study the treatment of poststroke depression and insomnia using varied repetitive transcranial magnetic stimulation (rTMS) frequencies alongside paroxetine. Aim to enhance rTMS effectiveness for depression, insomnia, neurological impairment, and daily living skills.

Methods: Ninety poststroke depression (PSD) patients were randomly divided into a low-frequency group (low-frequency rTMS + enteric-coated paroxetine), a high-frequency group (high-frequency rTMS + enteric-coated paroxetine), and a control group (sham stimulation + enteric-coated paroxetine).

SERS Performance Factor: A Convenient Parameter for the Enhancement Evaluation of SERS Substrates.

Surface-enhanced Raman spectroscopy (SERS), with molecular fingerprint information and single-molecule sensitivity, has been widely used for qualitative and quantitative analysis in various fields. Plenty of nanostructured plasmonic materials have been fabricated to achieve high SERS activity. Currently, great difficulty lies in evaluating the SERS performance among substrates, making it difficult to standardize.

Protective effects of intrathecal injection of AAV9-RabGGTB-GFP in SOD1 mice.

Introduction: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that widely affects motor neurons of the CNS. About 20% of patients with ALS have familial ALS (fALS). One of the classic models of ALS are SOD1 mice.

Effects of Butyphthalide Combined with Idebenone on Inflammatory Cytokines and Vascular Endothelial Functions of Patients with Vascular Dementia.

Objective: To determinate the clinical effect of butyphthalide combined with idebenone in the treatment of vascular dementia (VD) and the influence on inflammatory cytokines and vascular endothelial functions.

Study Design: Clinical comparative study.

Place And Duration Of Study: Department of Neurology, Baoding First Central Hospital, from June 2017 to June 2018.