Potential impact of organophosphate esters on thyroid eye disease based on machine learning and molecular docking.

Organophosphate esters (OPEs) are widely used as flame retardants and plasticizers in daily commodities and building materials. Some OPEs, acting as agonists of the thyroid-stimulating hormone receptor (TSHR), may contribute to the development of thyroid eye disease (TED). This study analyzes the serum and urine of patients and control groups, using machine learning and molecular docking to investigate the potential impact of OPEs on TED.

Environmental behavior and risk of the emerging organic contaminants halogenated carbazoles in chemical industrial park clusters.

Polyhalogenated carbazoles (PHCZs) are emerging organic contaminants and have attracted extensive concern because of their widespread occurrence and dioxin-like toxicity. However, the distribution characteristics, environmental behavior, and fate of PHCZs are still poorly understood. In this study, 74 composite environmental samples from 21 Chinese cities were collected around industrial parks in the Yangtze River Delta.

p-Phenylenediamines and p-phenylenediamine quinone derivatives in rubber consumer products and typical urban dust: Sources, transformation profiles, and health risks.

N,N'-Substituted p-phenylenediamines (PPDs) are widely used as antioxidants in the rubber industry and are released into the environment in large quantities during the production and use of rubber products. We quantified PPDs and PPD quinone derivatives (PPD-Qs) in rubber consumer products, including car tires, rubber belts, rubber gloves, rubber cables, and rubber hoses, to obtain information on the degree of weathering over time during their use. Additionally, we investigated the occurrences and sources of PPDs and PPD-Qs in dust samples collected from four typical urban environments (roads, parking lots, automotive repair shops, and residences).

Organophosphate ester exposure in nail salons: Health implications for workers.

Organophosphates esters (OPEs) have become a preferred alternative in nail polish as plasticizers due to health concerns over previously used additives like dibutyl phthalate. However, the true extent of nail technicians' exposure to OPEs is largely unknown. This study shows that nail salon workers are significant exposed to OPEs, with varied concentrations found in air, dust, masks, and urine.

Distributions and transformation of polyhalogenated carbazoles in environmental matrices contaminated by printing and dyeing plants.

As emerging organic contaminants, Polyhalogenated carbazoles (PHCZs) have caused wide concerns due to their wide distribution in the environment and dioxin-like toxicity. Nevertheless, research on the distribution and formation mechanisms of PHCZs in polluted environment of printing and dyeing plants is lacking. Here, 11 PHCZs were detected in samples from the Cao'e River, China, a typical river heavily polluted by printing and dyeing.

A Review of Distribution and Profiles of HBCD in Different Environmental Media of China.

Hexabromocyclododecane (HBCD) is the most important flame retardant that has been used in Expanded Polystyrene foam and Extruded Polystyrene foam in the past forty years across the world. China was the major producer and user of HBCD, and the total HBCD production was about 0.3 million tons.

Occurrence and Formation Mechanism of PCDD/Fs and SCCPs in Chlorinated Paraffin Products.

Polychlorinated dibenzo--dioxins and dibenzofurans (PCDD/Fs) and short-chain chlorinated paraffins (SCCPs) can be formed during the production of chlorinated paraffins (CPs). Detection and accurate quantification of PCDD/Fs in CPs are challenging because of their matrix complexity. Therefore, the occurrence and formation mechanisms of PCDD/Fs from CPs have not been studied extensively in the past.

Determination of Hexabromocyclododecane in Expanded Polystyrene and Extruded Polystyrene Foam by Gas Chromatography-Mass Spectrometry.

A gas chromatography-mass spectrometry (GC/MS) method for the determination of hexabromocyclododecane (HBCD) in expanded polystyrene and extruded polystyrene foam (EPS/XPS) was developed. The EPS/XPS samples were ultrasonically extracted with acetone and the extracts were purified by filtration through a microporous membrane (0.22 μm) and solid-phase extraction.