Publications by authors named "Tiana Ti"

Plasmodium knowlesi, a simian malaria parasite responsible for all recent indigenous cases of malaria in Malaysia, infects humans throughout Southeast Asia. There are two genetically distinct subpopulations of Plasmodium knowlesi in Malaysian Borneo, one associated with long-tailed macaques (termed cluster 1) and the other with pig-tailed macaques (cluster 2). A prospective study was conducted to determine whether there were any between-subpopulation differences in clinical and laboratory features, as well as in epidemiological characteristics.

View Article and Find Full Text PDF
Article Synopsis
  • In Southeast Asia and northern Australia, infections are common but often misdiagnosed, leading to high mortality rates of up to 50%.
  • A 2018 pilot study involved 100 patients with infection symptoms at Kapit Hospital in Malaysia, using three diagnostic methods—including PCR and rapid testing—to detect infections.
  • The study found that while the individual diagnostic tests had low sensitivity (25-44%) compared to the gold standard of bacterial culture, they demonstrated high specificity (93-98%), indicating a need for more sensitive diagnostics for better disease detection.
View Article and Find Full Text PDF