Tuning the Energetic Performance of CL-20 by Surface Modification Using Tannic Acid and Energetic Coordination Polymers.

The energetic performance of hexanitrohexaazaisowurtzitane (CL-20) was modulated with two energetic coordination polymers (ECPs), [Cu(ANQ)(NO)] and [Ni(CHZ)](ClO), in this study by a two-step method. First, tannic acid polymerized in situ on the surface of CL-20 crystals. Then, [Cu(ANQ)(NO)] and [Ni(CHZ)](ClO) were hydrothermally formed on the surface of CL-20/TA, respectively.

Surveillance-based evidence: elimination of schistosomiasis as a public health problem in the Peoples' Republic of China.

Background: A steady progress on schistosomiasis control in the Peoples' Republic of China (P.R. China) was achieved and broadened into the twelve-year medium and long term national plan (MLNP) which marled the implementation of an integrated control strategy across all endemic areas in P.

[Thinking on the control strategy at schistosomiasis elimination stage in China].

This paper reviews the evolution of the schistosomiasis control strategy in China at various stages after the founding of the People's Republic of China, and analyzes the roles and main problems of the schistosomiasis control strategy at different stages. At the end stage of schistosomiasis elimination, the integrated strategy with emphasis on infectious source control should be continued to be sustained and the problems regarding the implementation of this integrated strategy are analyzed. In addition, the countermeasures to solve these problems are proposed.

[Upholding Chinese spirit on schistosomiasis control in the new era to accelerate the progress towards schistosomiasis elimination in China].

China is one of the schistosomiasis-endemic countries with the highest burden of disease across the world. Following the control efforts for over 60 years, great successes have been achieved in schistosomiasis control in the country, and the control program is moving towards transmission interruption and elimination. To commemorate the 60th anniversary of publishing Chairman Mao Zedong's two poems entitled "", a series of activities that disseminate schistosomiasis control achievements have been conducted in China throughout 2018, including the development of Chinese spirit on schistosomiasis control in the new era.

[Investigation of snails in Anhui Province in 2016].

Objective: To investigate the status of snails in Anhui Province in 2016, so as to provide the evidence for formulating the 13th Five-Year Plans for Schistosomiasis Control.

Methods: In 2016, a snail survey was conducted in Anhui Province according to the , covering all snail habitats or historical snail habitats and suspected environments of snail breeding, and the results of the survey were analyzed.

Results: In 2016, 22 848 environments were surveyed, and no schistosome-infected snails were found.

[Application of infrared camera technique in investigation of wild animals as infectious source of schistosomiasis].

Objective: To investigate the species and activities of wild animals infected with schistosome in hilly and mountain areas by using an infrared camera technique, so as to provide the evidence for the surveillance of schistosomiasis in these areas.

Methods: Six infrared cameras were selected and placed in 6 environments of the risk monitoring points of schistosomiasis in Shitai County in Anhui Province. The species and activities of the wild animals in the 6 environments were observed through the photographs and videos taken by the cameras.

Spatio-temporal pattern of schistosomiasis in Anhui Province, East China: Potential effect of the Yangtze River - Huaihe River Water Transfer Project.

Anhui Province has been one of typical epidemic areas of schistosomiasis in East China as a wide range of large lake and marshland regions provide an ideal environment for growth and reproduction of the intermediate snail host. With the completion of the Yangtze River-Huaihe River Water Transfer Project (YHWTP), launched by the end of 2016, the epidemic areas are expected to expand and controlling schistosomiasis remains a challenge. Based on annual surveillance data at the county level in Anhui for the period 2006-2015, spatial and temporal cluster analyses were conducted to assess the pattern of risk through spatial (Local Moran's I and flexible scan statistic) and space-time scan statistic (Kulldorff).

[Evaluation standards and application for photography of schistosomiasis control theme].

Objective: To set up and apply the evaluation standards for photography of schistosomiasis control theme, so as to offer the scientific advice for enriching the health information carrier of schistosomiasis control.

Methods: Through the literature review and expert consultation, the evaluation standard for photography of schistosomiasis control theme was formulated. The themes were divided into 4 projects, such as new construction, natural scenery, working scene, and control achievements.

[Prevalence and Control of Parasitic Zoonoses].

At present, parasitic zoonoses in China are characterized by the reappearance of traditional parasitic zoonoses and constant emergence of new ones, which makes the prevention and control more difficult. In this review, we introduce the classification, epidemiological features, the endemic factors of the infection, as well as the principles and strategies for control, in the aim to provide hints on the control of such diseases in the future.

[Investigation on endemic situation of schistosomiasis in infection-controlled regions in Anhui Province].

Objective: To understand the epidemic situation of schistosomiasis in 27 counties (cities, districts) that reached the criteria of schistosomiasis infection controlled in Anhui Province.

Methods: According to the requirement of The National Assessment Scheme of Schistosomiasis, 81 administrative villages where the schistosomiasis epidemic situation was relatively heaver in above-mentioned 27 counties (1 village per town, 3 towns per county) were sampled and investigated.

Results: From 2012 to 2014, 81 villages were investigated, and 34,293 residents received the serum examinations, and 1,086 were positive with a positive rate of 3.

[Evaluation on molluscicidal effect of chlorosalicylicamide on Oncomelania hupensis in schistosomiaisis endemic areas of eight provinces in China].

Objective: To evaluate the effects of a novel molluscicide, the salt quinoid-2', 5-dichloro-4'-nitrosalicylanilide from niclosamide (LDS), with 10% wettable powder, in main schistosomiasis epidemic areas of China, including Hunan, Jiangxi, Hubei, Anhui, Jiangsu, Sichuan, Yunnan and Zhejiang Province.

Methods: In the immersion test, 6 effective concentrations of 10% LDS were tested respectively: 0.1, 0.

[Investigation on human Cryptosporidium infection in local area of Anhui Province].

Objective: To investigate the status of Cryptosporidium infection in the population in the local area of Anhui Province, and discuss the risk factors of the infection, so as to provide the evidence for the prevention and treatment of cryptosporidiosis.

Methods: Qianshan County and Lingbi County of Anhui Province were selected as investigation spots, and the oocysts of Cryptosporidium in the feces of the investigation objects and the specific IgG antibody against Cryptosporidium in the serum were checked by using the pathogenic modified acid fast staining method and ELISA, respectively, so as to determine the status of Cryptosporidium infection in these investigation objects. At the same time, the questionnaire surveys were conducted in the investigation objects so as to know about the risk factors of Cryptosporidium infection.

[Research progress of taxonomy and discrimination techniques of Oncomelania hupensis].

Oncomelania hupensis, which plays an important role in the transmission of schistosomiasis japonica, is the only intermediate host of Schistosoma japonicum, and carrying out studies on its subspecies differentiation and genetic variation will have an important significance for schistosomiasis control. In this paper, the research progress of taxonomy and discrimination techniques of O. hupensis is reviewed at four levels, namely the morphological level, the cellular level, the protein level, and the DNA molecule level, and DNA sequencing technology is considered as the ideal taxonomy and discrimination technique of O.

[Survey of endemic situations in schistosomiasis transmission controlled or interrupted regions in Anhui Province].

Objective: To understand the variation rules of schistosomiasis endemic situation before and after schistosomiasis transmission controlled or interrupted, so as to provide the evidence for the consolidation of control achievements.

Methods: In Anhui Province, 3 counties reaching the criteria of schistosomiasis transmission controlled or interrupted were selected and their historical endemic data were collected and analyzed statistically from 10 years before the schistosomiasis transmission controlled to 2008.

Results: In Tianchang City, the Oncomelania hupensis snail area was 3.

[The evidences for formulation of schistosomiasis control and elimination criteria: results from a large scale of retrospective investigations].

In this study, we summarized the results from the retrospective investigation on endemic situation of schistosomiasis that was implemented in nine provinces (autonomous region), China in 2009, demonstrated the role of these retrospective investigations in accelerating the progress of schistosomiasis control in China, and clarified the great significance of the investigation for summarizing the experiences for the control of schistosomiasis, and analyzing the changing patterns and affecting factors of endemic status of schistosomiasis in China. In addition, these retrospective investigations provide reliable evidence for revising the Criteria of Schistosomiasis Control and Elimination, and for the more accurate and scientific assessment of the effectiveness of schistosomiasis control in China.

Fine scale Spatial-temporal cluster analysis for the infection risk of Schistosomiasis japonica using space-time scan statistics.

Background: Marching towards the elimination of schistosomiasis in China, both the incidence and prevalence have witnessed profound decline over the past decades, with the strategy shifting from morbidity control to transmission control. The current challenge is to find out hotspots of transmission risk for precise targeted control in low-prevalence areas. This study assessed the risk at the village level, using the spatial and temporal characteristics of Schistosomiasis japonica in Anhui province from 2006 to 2012.

[Spatial-temporal analysis on the distribution of infected snail at the village level in Anhui province, 2006-2012].

Objective: The characteristics of spatial-temporal distribution on infected snails were analyzed at the village level in Anhui province, 2006-2012.

Methods: Data on the distribution of infected snails from 2006 to 2012 in Anhui province was collected. Spatial database was established by ArcGIS 9.

[Application of space-time scan statistics in early warning of distribution of schistosome infected Oncomelania hupensis snails].

Objective: To explore the application of space-time scan statistics in the early warning of distribution of schistosome infected Oncomelania hupensis snails.

Methods: The data of distribution of infected snails in Anhui Province from 2006 to 2012 were collected, and a spatial database was established by ArcGIS 9.3.

HIV and intestinal parasite co-infections among a Chinese population: an immunological profile.

Background: Parasite infections often result in a switch of the human body's predominant immune reaction from T-helper 1 (Th1)-type to Th2-type. Hence, parasite infections are widely expected to accelerate the progression of human immunodeficiency virus (HIV) infections to acquired immunodeficiency syndrome (AIDS). In the People's Republic of China, both parasitic diseases and AIDS are epidemic in certain rural areas, and co-infections are relatively common.

Value of 3.0 T diffusion-weighted imaging in discriminating thecoma and fibrothecoma from other adnexal solid masses.

Background: To investigate the value of diffusion-weighted imaging (DWI) at 3.0 T (3T), and especially the apparent diffusion coefficient (ADC), in discriminating ovarian thecoma from other adnexal solid masses.

Methods: Eighteen thecomas or fibrothecomas, 14 ligamentous leiomyomas, and 24 other ovarian solid tumors underwent prospective DWI magnetic resonance imaging (MRI) in addition to routine MRI on a 3T MRI machine.

Identifying host species driving transmission of schistosomiasis japonica, a multihost parasite system, in China.

Understanding disease transmission dynamics in multihost parasite systems is a research priority for control and potential elimination of many infectious diseases. In China, despite decades of multifaceted control efforts against schistosomiasis, the indirectly transmitted helminth Schistosoma japonicum remains endemic, partly because of the presence of zoonotic reservoirs. We used mathematical modeling and conceptual frameworks of multihost transmission ecology to assess the relative importance of various definitive host species for S.

[Research progress on transmission capacity of reservoir host of Schistosoma japonicum].

This paper reviews the researches related to the reservoir hosts of Schistosoma japonicum, including bovine, sheep, dog, cat and wild mouse. Combined with the implementation of the comprehensive control strategy with an emphasis on infection source control in current, it puts forward several future research directions under the condition that the effects of people and bovine as infection sources weakened gradually, such as revaluation on the actual transmission capacity of non-bovine livestock, for example, sheep, dog, pig and wild mouse, as well as discussion on some transmission threshold values in the infection link of Oncomelania snails.

[Study on assessing system for endemicity of schistosomiasis].

Objective: To establish a scientific, objective and operational assessing system for schistosomiasis endemicity, so as to provide a scientific evidence for revising the current Criteria for Control and Elimination of Schistosomiasis in China (GB 15976-2006).

Methods: A questionnaire was designed based on reference review and 20 scientists working in the field of schistosomiasis control, research or management were investigated by using the Delphi method. The importance of each index reflecting the endemicity of schistosomiasis was scored by each scientist.