Use of Vacuum-Assisted Wound Closure and Tissue Expansion in Revision Cranioplasty for a Large-Sized Composite Defect in a Child.

Cranioplasty is generally defined as the procedure to reconstruct cranial bone defect arising from congenital or acquired process. As a surgical remedy, it can restore the function of original anatomical structure and produce a satisfactory cosmetic outcome. Although with available options for treating pediatric cranioplasty, large format (ie, >25 cm) cranioplasty of the aborted one with a composite defect is still a challenging procedure for plastic surgeons.

Establishment of intramedullary spinal cord glioma model in rats.

Background: Treating intramedullary spinal cord gliomas is a big challenge because of limited options, high recurrence rate and poor prognosis. An intramedullary glioma model is prerequisite for testing new treatments. This paper describes the establishment of a rodent intramedullary glioma model and presents functional progression, neuroimaging and histopathological characterization of the tumour model.