Publications by authors named "Tian-Shun Lai"
Background: Subsequent neutrophil (polymorphonuclear neutrophil [PMN])-predominant inflammatory response is a predominant feature of ventilator-induced lung injury (VILI), and mesenchymal stem cell (MSC) can improve mice survival model of endotoxin-induced acute lung injury, reduce lung impairs, and enhance the repair of VILI. However, whether MSC could attenuate PMN-predominant inflammatory in the VILI is still unknown. This study aimed to test whether MSC intervention could attenuate the PMN-predominate inflammatory in the mechanical VILI.
View Article and Find Full Text PDFObjective: To study the effect of continuous hemofiltration (CH) on the prognosis of multiple organ dysfunction syndrome (MODS) after acute myocardial infarction (AMI) in elderly patients.
Methods: Thirty-four elderly patients with MODS after AMI admitted to intensive care unit (ICU) were grouped into continuous hemofiltration (CH) group and non-CH (NCH) group. The Acute Physiology and Chronic Health Evaluation (APACHEII) scores and Marshall scores were assessed upon admission in ICU and 7 days after the admission.
Background: Nitric oxide (NO) plays an important role in acute lung injury (ALI), acute respiratory distress syndrome (ARDS), and in ventilator-induced lung injury (VILI). A change in the balance of endothelin-1 (ET-1) and NO in the ALI/ARDS can also add to these problems. However, the profile of ET-1 and the balance of ET-1 and NO are still unknown in a VILI model.
View Article and Find Full Text PDF[Effect of mechanical ventilation with different tidal volume on small intestine in dogs suffering from acute lung injury].
Zhongguo Wei Zhong Bing Ji Jiu Yi Xue
October 2008
Objective: To compare the effect of different tidal volume (VT) on intestinal tissue in oleic acid-induced acute lung injury (ALI) dogs undergoing mechanical ventilation (MV).
Methods: ALI was induced with oleic acid in dogs. While all of them were undergoing MV, they were randomized into two groups: low VT group (n=6), with VT 6 ml/kg, positive end-expiratory pressure (PEEP) 10 cm H2O (1 cm H2O= 0.
Article Synopsis
- The study evaluates the effectiveness of the MELD (Model for End-Stage Liver Disease) score in predicting early outcomes, including complications and mortality, after liver transplantation in patients with end-stage liver disease.
- Among 87 recipients analyzed, a significant portion (20.7%) experienced severe complications, with survival rates of 89.7% at 28 days and 88.5% at three months; higher MELD scores were linked to worse outcomes.
- The findings suggest that a MELD score above 25 is a key indicator of increased risk for severe complications and mortality following liver transplantation.