Pyogenic liver abscess in pediatric populations in beijing (2008-2023).

Background: Data on pyogenic liver abscess (PLA) of children in China have been limited. We aimed to summarize the clinical feather, microbiological characteristics, management, and outcome of PLA in children.

Method: We retrospectively reviewed PLA cases from January 2008 to June 2023 at Beijing Children's Hospital.

Group A Streptococcal meningitis in children: a short case series and systematic review.

Background: Group A streptococcal(GAS) meningitis is a severe disease with a high case fatality rate. In the era of increasing GAS meningitis, our understanding about this disease is limited.

Purpose: To gain a better understanding about GAS meningitis.

A critical review on graphene oxide membrane for industrial wastewater treatment.

An important way to promote the environmental industry's goal of carbon reduction is to promote the recycling of resources. Membrane separation technology has unique advantages in resource recovery and advanced treatment of industrial wastewater. However, the great promise of traditional organic membrane is hampered by challenges associated with organic solvent tolerance, lack of oxidation resistance, and serious membrane fouling control.

MRI-guided microwave ablation and albumin-bound paclitaxel for lung tumors: Initial experience.

Magnetic resonance-guided microwave ablation (MRI-guided MWA) is a new, minimally invasive ablation method for cancer. This study sought to analyze the clinical value of MRI-guided MWA in non-small cell lung cancer (NSCLC). We compared the precision, efficiency, and clinical efficacy of treatment in patients who underwent MRI-guided MWA or computed tomography (CT)-guided microwave ablation (CT-guided MWA).

Effect of different carbon sources on sulfate reduction and microbial community structure in bioelectrochemical systems.

Microbial electrolysis cells (MECs) have rapidly developed into a promising technology to treat sulfate-rich wastewater that lacks electron donors. Hence, a better understanding of the effect on the microbial community structure caused by different sources in bioelectrochemical systems is required. This study sought to investigate the effect of different carbon sources (NaHCO, ethanol, and acetate were employed as sole carbon source respectively) on the performance of sulfate-reducing biocathodes.

Fever of unknown origin (FUO) in children: a single-centre experience from Beijing, China.

Objective: To date, there is no standard diagnostic practice to identify the underlying disease-causing mechanism for paediatric patients suffering from chronic fever without any specific diagnosis, which is one of the leading causes of death in paediatric patients. Therefore, we aimed this retrospective study to analyse medical records of paediatric patients with fever of unknown origin (FUO) to provide a preliminary basis for improving the diagnostic categories and facilitate the treatment outcomes.

Design: A retrospective study.

Antibiotics prescription for targeted therapy of pediatric invasive pneumococcal diseases in China: a multicenter retrospective study.

Background: Streptococcus pneumoniae (S. pneumoniae) is a major cause of bacterial meningitis, septicemia and pneumonia in children. Inappropriate choice of antibiotic can have important adverse consequences for both the individual and the community.

Endoscopic treatment for acute appendicitis with coexistent acute pancreatitis: Two case reports.

Background: Appendectomy is the procedure of choice for the treatment of acute appendicitis. However, surgery may not be appropriate for patients with coexisting severe illness or comorbidities such as acute pancreatitis (AP). Endoscopic retrograde appendicitis treatment (ERAT) may be a novel alternative to surgery for treating such patients where existing medical therapies have failed.

Characteristics of Pediatric Recurrent Bacterial Meningitis in Beijing Children's Hospital, 2006-2019.

Background: Few data on recurrent bacterial meningitis (RBM) in children are available. Here, we estimated the frequency of RBM in children and investigated the predisposing conditions, etiology, and clinical characteristics of RBM in children.

Methods: Cases of RBM in the Beijing Children's Hospital medical record database between January 2006 and December 2019 were collected.

Clinical Characteristics and Outcome Analysis of 94 Children With Brain Abscess in Beijing: A Single-center Retrospective Study.

Background: There are limit studies about pediatric brain abscess in China. The aim of this study was to analyze clinical characteristics and outcomes of pediatric brain abscess in recent years in China.

Methods: The clinical information of children with brain abscess hospitalized in Beijing Children's Hospital between January 1, 2007 and December 31, 2016 were retrospectively reviewed.

The application of magnetic resonance imaging-guided microwave ablation for lung cancer.

Context: It is necessary to explore a minimally invasive, effective, and efficient treatment for those lung cancer patients who are poor candidates for surgery.

Aim: This study aimed to investigate the application of microwave ablation (MWA) in the treatment of lung cancer.

Settings And Design: A total of 43 patients with 44 pulmonary lesions were examined following identical procedures before being randomly divided into two groups.

Bouveret syndrome: A case report.

Background: Bouveret syndrome is a rare complication of cholelithiasis, with only 315 cases reported in the literature between 1967 and 2016. Delay in diagnosis is associated with a high mortality rate. Diagnosis is based upon clinical manifestations, gastroscopy, and imaging studies such as abdominal computed tomography and magnetic resonance cholan-giopancreatography.

Synthesis of Au@TiO core-shell nanoparticles with tunable structures for plasmon-enhanced photocatalysis.

Plasmonic metal-semiconductor nanocomposites, especially those with core-shell nanostructures, have received extensive attention as they can efficiently expand light absorption and accelerate electron-hole separation thus improving the photocatalytic efficiency. However, controlled synthesis and structure manipulation of plasmonic metal-semiconductor nanocomposites still remain a significant challenge. Herein, a simple and universal method has been developed for the preparation of plasmonic Au@TiO core-shell nanoparticles.

miR-16 regulates proliferation and invasion of lung cancer cells via the ERK/MAPK signaling pathway by targeted inhibition of MAPK kinase 1 (MEK1).

Objective: The ERK/MAPK signaling pathway regulates cell proliferation and invasion. MAPK kinase 1 (MEK1) is a protein kinase upstream of ERK that can activate the pathway. Expression of microRNA (miR)-16 in lung cancer tissues is decreased.

The diagnostic value of metagenomic next-generation sequencing for identifying Streptococcus pneumoniae in paediatric bacterial meningitis.

Background: There is currently no research on the diagnostic value of metagenomic next-generation sequencing (mNGS) for a single pathogens in CSF. The aim of this study was to analyse the value of mNGS for identifying Streptococcus pneumoniae (S. pneumoniae) in paediatric bacterial meningitis.

Optimal management after paediatric lumbar puncture: a randomized controlled trial.

Background: To evaluate whether a shorter time of lying supine without a pillow and fasting for solids and liquids (LSFSL) after a lumbar puncture (LP) is associated with a higher risk of post-lumbar puncture headache (PLPH) and post-lumbar puncture lower back pain (PLPBP) in a randomized, assessor-blinded, controlled trial.

Methods: Paediatric patients who underwent their first LP after hospital admission were randomly allocated to either the group with half an hour of LSFSL (0.5 h LSFSL) or 4 h of LSFSL (4 h LSFSL) immediately after LP.

Evaluation of next-generation sequencing for the pathogenic diagnosis of children brain abscesses.

In this study, we applied metagenomic next-generation sequencing (mNGS) to detect the causative pathogens in brain abscess samples from 4 pediatric patients. NGS could offer unbiased sequencing and rapid diagnosis of causative pathogens, moreover, it could detect multiple pathogenic microorganisms from abscess samples. In our study, Fusobacterium nucleatum, and Streptococcus intermedius or combinations of them were found in 3/4 of polymicrobial brain abscesses.

[Performance of Treating Straw and Animal Manure Mixture by an Integrated Process of Thermo-alkali-bi-enzyme Hydrolysis-anaerobic Digestion and Conditions of High Methane Yield].

To obtain a high methane yield during the anaerobic digestion of a straw and animal manure mixture, an integrated process of thermo-alkali-bi-enzyme hydrolysis-anaerobic digestion was proposed. A mixture of corn straw and cattle manure was selected as the experimental object. A higher dissolution efficiency of cellulose, hemicellulose, and protein in the thermo-alkali pretreatment, dosages and hydrolysis times of cellulase and protease in the bi-enzyme hydrolysis, and the methane yield and biogas production cycle in the anaerobic digestion with mixed slurry and hydrolysates were investigated respectively.

Characteristics and outcomes of cryptococcal meningitis in HIV seronegative children in Beijing, China, 2002-2013.

Background: Data regarding HIV-seronegative pediatric patients with cryptococcal meningitis (CM) have been very limited.

Methods: We retrospectively reviewed non-HIV-infected in patients with CM from January 2002 through December 2013 in Beijing Children's Hospital. Records of the all patients were obtained and compared.

Possible molecular mechanism underlying cadmium-induced circadian rhythms disruption in zebrafish.

This study was aimed to explore the mechanisms underlying cadmium-induced circadian rhythms disruption. Two groups of zebrafish larvae treated with or without 5 ppm CdCl were incubated in a photoperiod of 14-h light/10-h dark conditions. The mRNA levels of clock1a, bmal1b, per2 and per1b in two groups were determined.

Complete genome sequence and comparative genome analysis of the Paenibacillus mucilaginosus K02.

Aim: Paenibacillus mucilaginosus (P. mucilaginosus) K02 is implicated in mineral weathering. However, relevant molecular mechanisms remain obscure.

Stochastic effects in adaptive reconstruction of body damage: implied the creativity of natural selection.

After an injury occurs, mechanical/biochemical loads on muscles influence the composition and structure of recovering muscles; this effect likely occurs in other tissues, cells and biological molecules as well owing to the similarity, interassociation and interaction among biochemical reactions and molecules. The 'damage and reconstruction' model provides an explanation for how an ideal cytoarchitecture is created by reducing components not suitable for bearing loads; in this model, adaptive changes are induced by promoting the stochasticity of biochemical reactions. Biochemical and mechanical loads can direct the stochasticity of biochemical reactions, which can in turn induce cellular changes.

Approaches to the evaluation of malaria elimination at county level: case study in the Yangtze River Delta region.

As the progress on transition from malaria control to malaria elimination in the People's Republic of China (P.R. China), four counties/districts, namely Zhabei District and Songjiang District of Shanghai municipality, and Anji County and Haiyan County of Zhejiang Province, representatives of the Yangtze River Delta region, were included in the pilot project of the national malaria elimination programme in P.