Synopsis of recent research by authors named "Tian-Jun Chen"
- Tian-Jun Chen's recent research focuses primarily on the molecular mechanisms underlying lung cancer, with a particular emphasis on the roles of microRNAs and long non-coding RNAs in tumorigenesis and cancer progression.
- Key findings include demonstrating how microRNA-665 promotes cell proliferation and inhibits apoptosis in lung squamous cell carcinoma, and how LncRNA HOTAIRM1 reduces proliferation and invasion in lung adenocarcinoma through specific signaling pathways.
- Additionally, Chen explores the impact of the Klotho gene on drug resistance in lung cancer and evaluates the effects of natural compounds on enhancing the efficacy of standard chemotherapy agents like cisplatin, highlighting potential therapeutic strategies against lung cancer.
