Publications by authors named "Tian-Jing Lu"
[Role of CD2-associated protein and nephrin expression in multilocular cystic renal cell carcinoma].
Zhonghua Yi Xue Za Zhi
March 2009
Objective: To investigate the role of CD2-associated protein (CD2AP) and nephrin expression in the multilocular cystic renal cell carcinoma (MCRCC) METHODS: Seventy four specimens of renal lesions, including 29 cases of MCRCC, 32 case of clear cell renal cell carcinoma (CCRCC), and 13 cases of simple renal cyst (SRC), were collected during operation. Immunohistochemistry was used to detect the CD2AP expression. Five wax lumps from each of the 3 groups of specimen, totally 15, were randomly selected to undergo re-sectioning and immunohistochemistry so as to compare the levels of staining intensity and location of expression of CD2AP and nephrin in the same sections.
View Article and Find Full Text PDFPurpose: The most common genitourinary malignancy in China is bladder transitional cell carcinoma (TCC). Early diagnosis of new and recurrent bladder cancers, followed by timely treatment, will help decrease mortality. There are currently no satisfactory markers for bladder cancer available in clinics.
View Article and Find Full Text PDFArticle Synopsis
- The study examines how severe acute pancreatitis (SAP) affects intestinal immune function in rats and evaluates the impact of L-arginine as a treatment.
- Key findings show that SAP leads to increased plasma endotoxin levels and decreased proportions of specific T lymphocytes, indicating a suppression of intestinal immunity.
- L-arginine treatment appears to enhance intestinal immune function by reducing endotoxin levels, increasing certain T cell proportions, and boosting immunoglobulin A (SIgA) levels in the cecum.
[Laminin and its alpha 6 integrin receptor in the regulation of human hepatocellular carcinoma cell phenotypes].
Zhonghua Zhong Liu Za Zhi
January 2003
Objective: To study the role of integrin alpha 6 in cell attachment, spread, survival/proliferation and differentiation of human hepatocellular carcinoma (HCC) BEL-7402 cells on various substrates by monoclonal antibody against the extracellular domain of alpha 6 subunit (IA6ED McAb).
Methods: The effect of McAb on attachment and spread of BEL-7402 cells on LN or FN substrate was examined. MTT analysis was used to examine the cell survival/proliferation, gelatin zymography to the matrix metalloproteinases (MMPs) secreted by BEL-7402 cells, and microparticle immunoabsorbent kit to AFP secretion while the cells were cultured on LN-, FN- or Matrigel-coated substrates.