[Retracted] Antitumor‑ and apoptosis‑inducing effects of pomolic acid against SK‑MEL‑2 human malignant melanoma cells are mediated via inhibition of cell migration and sub‑G1 cell cycle arrest.

Following the publication of the above paper, a concerned reader drew to the Editor's attention that several figures (Figs. 3‑8 inclusive) contained apparent anomalies, including repeated patternings of data within the same figure panels. After having conducted an independent investigation in the Editorial Office, the Editor of has determined that the above paper should be retracted from the Journal on account of a lack of confidence concerning the originality and the authenticity of the data.

C-type lectin receptor-mediated immune recognition and response of the microbiota in the gut.

C-type lectin receptors (CLRs) are powerful pattern-recognition receptors that discern 'self' and 'non-self' in our body and protect us from invasive pathogens by mediating immune recognition and response. The gastrointestinal tract is very important for the maintenance of homeostasis; it is the largest shelter for the billions of microorganisms in the body and CLRs play a crucial regulatory role in this system. This study focuses on several CLRs, including Dectin-1, Dectin-2, Dectin-3 and Mincle.

Antitumor‑ and apoptosis‑inducing effects of pomolic acid against SK‑MEL‑2 human malignant melanoma cells are mediated via inhibition of cell migration and sub‑G1 cell cycle arrest.

Malignant melanoma is the leading cause of mortality among the skin‑associated diseases because of its highly metastatic nature and lethality. The aim of the present study was to evaluate antitumor and apoptosis effects of pomolic acid, a pentacyclic triterpene, against SK‑MEL‑2 human malignant melanoma cells. Its effect on cell migration and cell cycle arrest were also studied.

ABT-737 sensitizes curcumin-induced anti-melanoma cell activity through facilitating mPTP death pathway.

In the current study, we studied the potential role of ABT-737, a novel Bcl-2 inhibitor, on curcumin-induced anti-melanoma cell activity in vitro. The associated mechanisms were also investigated. We demonstrated that ABT-737 significantly sensitized curcumin-induced activity against melanoma cells (WM-115 and B16 lines), resulting in substantial cell death and apoptosis with co-administration.

The effect of phytohormones on safflower regeneration plant.

Objective: To study the effect of phytohormones on the regeneration of safflower, in order to provide a foundation for the rapid propagation of safflower seeds and genetic transformation.

Methods: The experiment used the cotyledons as the explant and studied the influence of calli induction, differentiation and rooting by phytohormones.

Results: 1.