[Absorption of extractive Rhizoma Coptidis in rat everted gut scas].

Objective: Using in vitro everted gut seas to research the intestinal absorption of the extractive Rhizoma Coptidis at the different intestinal section and the different density.

Method: Berberine (BER) and palmatine (PAL) which are representative compositions of the extractive Rhizoma Coptidis in everted gut seas are detected by HPLC, and calculated the absorption parameter to describe the character of absorption.

Result: The absorption of BER and PAL is linearity in different intestine and different dose, and the square of coefficient correlation exceed 0.