Publications by authors named "Tian-Da Wang"
Article Synopsis
- The study aims to create a nomogram for early prediction of severe mycoplasma pneumoniae pneumonia (SMPP) in both pediatric and adult patients by analyzing 550 cases, classified into severe and non-severe groups.
- Various models were developed using clinical data, imaging, and radiomics features, assessed through different statistical methods, including logistic regression and AUC metrics.
- The integrated model showed strong predictive ability, particularly in testing cohorts, with a notable improvement when combining clinical and imaging features, demonstrating its effectiveness for identifying SMPP.
Purpose: This study aims to explore the value of clinical features, CT imaging signs, and radiomics features in differentiating between adults and children with Mycoplasma pneumonia and seeking quantitative radiomic representations of CT imaging signs.
Materials And Methods: In a retrospective analysis of 981 cases of mycoplasmal pneumonia patients from November 2021 to December 2023, 590 internal data (adults:450, children: 140) randomly divided into a training set and a validation set with an 8:2 ratio and 391 external test data (adults:121; children:270) were included. Using univariate analysis, CT imaging signs and clinical features with significant differences ( < 0.
Limited continuous replenishment of the mineralization medium is a restriction for in-situ solution-based remineralization of hypomineralized body tissues. Here, we report a process that generated amine-functionalized mesoporous silica nanoparticles for sustained release of biomimetic analog-stabilized amorphous calcium phosphate precursors. Both two-dimensional and three-dimensional collagen models can be intrafibrillarly mineralized with these released fluidic intermediate precursors.
View Article and Find Full Text PDFObjectives: In tissue regeneration research, the term "bioactivity" was initially used to describe the resistance to removal of a biomaterial from host tissues after intraosseous implantation. Hydraulic calcium silicate cements (HCSCs) are putatively accepted as bioactive materials, as exemplified by the increasing number of publications reporting that these cements produce an apatite-rich surface layer after they contact simulated body fluids.
Methods: In this review, the same definitions employed for establishing in vitro and in vivo bioactivity in glass-ceramics, and the proposed mechanisms involved in these phenomena are used as blueprints for investigating whether HCSCs are bioactive.