Publications by authors named "Tian Meijing"

Objective: To identify whether Banxia Xiexin Decoction (BXD) alleviates cerebral glucose metabolism disorder by intestinal microbiota regulation in APP/PS1 mice.

Methods: Forty-five 3-month-old male APP/PS1 mice were divided into 3 groups using a random number table (n=15 per group), including a model group (MG), a liraglutide group (LG) and a BXD group (BG). Fifteen 3-month-old male C57BL/6J wild-type mice were used as the control group (CG).

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Objective: To investigate the efficacy of Jinsiwei (a patented Chinese herbal compound) on learning and memory impairment, the number of synapses and synaptic plasticity-related structural and functional protein expression in mice with sporadic Alzheimer's disease (SAD) induced by streptozotocin.

Methods: Seventy-five C57/BL6J male mice were intracerebroventricularly injected with streptozotocin to establish the animal model of SAD. Mice were randomly divided into the model group (MG), donepezil group (DG), and the Jinsiwei high, medium, and low-dose groups (JH, JM, JL).

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Article Synopsis
  • The study aimed to assess the effectiveness of guidewire-assisted reduction technology, used with an upright posture, for correcting malpositioned catheters in the internal jugular vein during central venous catheterization.
  • During the research period, 99 patients were randomly split into two groups: a control group receiving only guidewire technology and an experimental group using both the guidewire method and upright posture.
  • Results indicated a significantly higher success rate in the experimental group (94.6%) compared to the control group (69.8%), suggesting that the combined approach is more effective for reducing malpositioned catheters.
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Background: Catheter jamming is an emerging and possibly underrated complication.

Objective: To find the criteria for determining if the catheter cannot be removed through the mechanical analysis of fracture tension and fracture strain (εf) of Peripheral Inserted Central Catheters (PICC).

Method: We removed 30 pieces of PICC catheters from patients and recorded the indwelling time.

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Article Synopsis
  • Shen-Zhi-Ling oral liquid (SZL) is an herbal treatment aimed at supporting heart and spleen health, specifically targeting early-stage dementia and Alzheimer's disease (AD) through neuroprotective mechanisms related to brain glucose metabolism.
  • The study utilized various methods, including LC-MS/MS, behavioral tests on transgenic mice, transmission electron microscopy, and micro-PET imaging, to evaluate SZL's effects on cognitive functions, brain structure, and glucose uptake.
  • Results indicated that SZL significantly improved cognitive deficits and reduced pathological damage associated with AD, enhancing glucose transport and signaling pathways (InR/PI3K/Akt) that are crucial for brain health.
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Objective: To compare the clinical application effects of peripherally inserted central catheter (PICC) and deep venous catheters placed through the lower limbs in adults with malignancy obviating the use of upper limb PICC.

Study Design: Descriptive study.

Place And Duration Of Study: Department of Oncology, Beijing Shijingshan Hospital, Capital Medical University, Beijing, China between February 2017 and February 2019.

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Ethnopharmacological Relevance: Shenzhiling oral liquid (SZL), a traditional Chinese medicine (TCM) compound, is firstly approved by the Chinese Food and Drug Administration (CFDA) for the treatment of mild to moderate Alzheimer's disease (AD). SZL is composed of ten Chinese herbs, and the precise therapy mechanism of its action to AD is far from fully understood.

Aim Of The Study: The purpose of this study was to observe whether SZL is an effective therapy for amyloid-beta (Aβ)-induced myelin sheath and oligodendrocytes impairments.

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