Publications by authors named "Tian Jinhui"
Background: Trastuzumab therapy for HER2-positive cancers is associated with cardiotoxicity. This umbrella review synthesizes evidence from systematic reviews and meta-analyses on cardioprotective interventions during trastuzumab treatment.
Methods: A comprehensive search was conducted in PubMed, Embase, Cochrane Library, and Web of Science.
Ethnopharmacological Relevance: Chinese patent medicine (CPM) is formulated using Chinese herbal medicines as raw materials according to prescribed methods and preparation processes. It is one of the most commonly used complementary and alternative therapies for insomnia in China. Dozens of CPMs have been applied in clinical settings to treat primary insomnia, and ample evidence has proven the efficacy and safety of various CPMs.
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- A large number of systematic reviews and meta-analyses have examined the impact of sodium intake on cardiovascular health, but the overall quality and consistency of these studies haven't been clearly summarized.
- An umbrella review was conducted to evaluate the strength of the evidence linking lower sodium intake to better cardiovascular outcomes, using rigorous quality assessment tools.
- The findings indicated that reducing sodium intake can significantly lower blood pressure and might reduce the risk of major cardiovascular events, especially in individuals with lower cardiovascular risk, with some benefits noted from using salt substitutes.
This systematic review and meta-analysis sought to assess whether ultra-high dose rate (UHDR) ion irradiations can induce the FLASH effect in animal models. A comprehensive search of the Web of Science, PubMed, and EMBASE databases was conducted from inception until March 20, 2023, to identify studies involving irradiated animals subjected to proton or carbon ion beams at varying dose rates. The research content should include various indicators that can reflect the effect and safety of radiation, such as survival, normal tissue toxicity, inflammatory response, tumor volume, etc Compared to conventional dose rate (CONV) ion irradiations, UHDR ion irradiations can significantly improve mouse survival (HR 0.
View Article and Find Full Text PDFStatins for the primary prevention of venous thromboembolism.
Cochrane Database Syst Rev
November 2024
Background: Venous thromboembolism (VTE) involves the formation of a blood clot in a vein, and includes deep venous thrombosis (DVT) or pulmonary embolism (PE). The annual incidence for VTE varies from 0.75 to 2.
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- - The study assessed the CARE-Radiology checklist's reliability and usability for evaluating radiological case reports, aiming to encourage its wider use and improvement.
- - Ten case reports from 2020 were reviewed by 26 experts from 10 different countries, measuring the checklist's effectiveness using statistical methods like Fleiss' Kappa and Cronbach's alpha.
- - Results showed moderate reliability, with a mean compliance rate of 61.8% for checklist items, and while most evaluators found it easy to use, certain areas need feedback for future enhancements.
Article Synopsis
- The study analyzed the effectiveness of antiviral drugs for treating severe influenza to aid in updating WHO clinical guidelines.
- Researchers searched various medical databases for randomized controlled trials involving hospitalized patients to compare antiviral medications against placebos and other treatments.
- Eight trials were ultimately included, with a total of 1,424 participants, leading to a network meta-analysis focusing on key outcomes like symptom alleviation time, hospitalization duration, and mortality rates.
Objective: To understand how reviewers select and prespecify outcomes for systematic reviews (SRs), the authors report on the outcomes used in SRs of pressure injury (PI) intervention and treatment and evaluate their completeness of prespecification.
Data Sources: The authors searched four electronic databases for SRs involving PI prevention and/or treatments.
Study Selection: Inclusion criteria were SRs and meta-analyses evaluating interventions for preventing or treating PI.
Top 100 cited research on COVID-19 vaccines: A bibliometric analysis and evidence mapping.
Hum Vaccin Immunother
December 2024
The outbreak of the COVID-19 has seriously affected the whole society, and vaccines were the most effective means to contain the epidemic. This paper aims to determine the top 100 articles cited most frequently in COVID-19 vaccines and to analyze the research status and hot spots in this field through bibliometrics, to provide a reference for future research. We conducted a comprehensive search of the Web of Science Core Collection database on November 29, 2023, and identified the top 100 articles by ranking them from highest to lowest citation frequency.
View Article and Find Full Text PDFBackground: We conducted an overview to assess immune adverse effects associated with the COVID-19 vaccine, guiding safer choices and providing evidence-based information to clinicians.
Methods: Forty-three studies on adverse effects of vaccines were reviewed from PubMed, Embase, and Web of Science. Single-arm meta-analyses estimated summary effects, incidence, presentation, etc.
Background: Despite fractures of Isolated Weber B being prevalent, there is a lack of clarity regarding the relative effectiveness of surgical versus conservative treatment. This systematic review and meta-analysis aimed to investigate the clinical effects and complications of surgical versus conservative treatment of the Isolated Weber B ankle fractures.
Methods: This study involved thorough searches across multiple electronic databases, including PubMed, Cochrane, Embase, and Web of Science, to identify all relevant publications on Isolated Weber B ankle fractures repaired through surgical versus conservative treatment.
Article Synopsis
- The study aimed to assess whether tranexamic acid (TXA) usage during total joint arthroplasty (TJA) in patients with a history of thromboembolic risks is connected to higher rates of death or postoperative issues.
- The researchers reviewed multiple studies up to May 2023, including randomized trials and cohort studies, and employed methods to ensure the quality of the data analyzed.
- The findings showed that TXA significantly decreases blood loss, transfusion rates, and unplanned readmission rates post-surgery, without increasing the risk of mortality or other complications, suggesting it's safe for high-risk patients.
Objective: Tension-type headache is the most common type of primary headache and results in a huge socioeconomic burden. This network meta-analysis (NMA) aimed to compare the efficacy and safety of simple analgesics for the treatment of episodic tension-type headache (ETTH) in adults.
Methods: We searched the Cochrane Library, PubMed, Web of Science, Embase, Chinese BioMedical Literature database and International Clinical Trials Registry Platform databases for eligible randomized clinical trials reporting the efficacy and/or safety of simple analgesics.
The objective of this study was to assess the quality and consistency of recommendations in clinical practice guidelines (CPGs) and expert consensus on paediatric cow's milk protein allergy (CMPA) to serve as a foundation for future revisions and enhancements of clinical guidelines and consensus documents. We conducted a comprehensive literature search across several databases, including the Chinese Biomedical Literature Database (CBM), PubMed, Embase, Web of Science, UpToDate, ClinicalKey, DynaMed Plus and BMJ Best Practice. We spanned the search period from the inception of each database through October 1, 2023.
View Article and Find Full Text PDFImportance: Large language models (LLMs) may facilitate the labor-intensive process of systematic reviews. However, the exact methods and reliability remain uncertain.
Objective: To explore the feasibility and reliability of using LLMs to assess risk of bias (ROB) in randomized clinical trials (RCTs).