Publications by authors named "Tiama Hamkins-Indik"
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Synopsis of recent research by authors named "Tiama Hamkins-Indik"
- Tiama Hamkins-Indik's research focuses on understanding cell behavior and epithelial dynamics through innovative microfluidic systems and techniques, particularly emphasizing the role of surface topography and molecular interactions in cell migration and tissue function.
- Key findings include the identification of a specific sequence in the tight junction adaptor protein ZO-1 crucial for actin binding, which regulates epithelial permeability, and the development of an automated robotic system for maintaining multi-organ chip viability for extended periods.
- The studies conducted demonstrate advancements in non-invasive methods to analyze transepithelial barrier function and the ability to study human enterovirus infections in a realistic intestinal environment using a gut-on-a-chip model, showcasing the potential for biomedical applications and drug testing.