Publications by authors named "Tiago Ramires"

Article Synopsis
  • The study aimed to compare COVID-19 patient characteristics, clinical management, and outcomes during the peak (weeks 10-16) and plateau (weeks 17-34) phases of the first pandemic wave in Portugal.
  • A total of 541 adult patients, mostly male with a median age of 65, were analyzed, showing no significant differences in age, initial health scores, and 28-day mortality between the two periods.
  • Key findings indicated fewer comorbidities, higher use of certain treatments (like vasopressors and invasive ventilation) during the peak, whereas the plateau saw increased use of different therapies like remdesivir and corticosteroids and shorter ICU stays.
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Retinitis is the most frequent manifestation of Cytomegalovirus (CMV) disease in patients with HIV infection. The virus reaches the retina by hematogenous spread, therefore patients with serum CMV load are at increased risk of developing CMV retinitis. The evolution of retinitis without specific treatment causes irreversible visual loss.

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A 23-year-old woman with fever, oral ulcers, arthalgias and weight loss of 2-week duration suddenly developed blurred vision, with reduced visual acuity, cotton wool exudates and retinal vascular tortuosity. Laboratory testing revealed anaemia, lymphopaenia, positive antinuclear antibody and high anti-dsDNA antibody titre with low complement components. There was no evidence of infection, clinching the diagnosis of lupus retinopathy.

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