Publications by authors named "Tiago Porfirio"
Eur J Pharm Sci
March 2021
Article Synopsis
- The study analyzes the rheological properties of common polymers and solvents used in creating amorphous solid dispersions through spray drying, focusing on copovidone, HPMC, HPMCAS, and Eudragit L100.
- HPMC and HPMCAS display shear thinning behavior, where viscosity decreases with increased shear rate, while Eudragit L100 behaves as a Boger fluid, maintaining constant viscosity.
- Copovidone acts as a Newtonian fluid with no elasticity, providing critical insights that can enhance the understanding and modeling of the spray drying process.
