[Systolic pressure variation as an earlier hypovolemia indicator and a guide for volume replacement with hypertonic and hyperoncotic solution in dogs].

Background And Objectives: Studies have introduced a new method for preload evaluation based on systolic pressure variation analysis (SPV) during mechanical ventilation. This research aimed at evaluating whether SPV and its delta down derived (ddown) are earlier hypovolemia indicators and guides for volume replacement with hypertonic and hyperoncotic solutions.

Methods: Twelve dogs were submitted to graded hemorrhage of 5% of their volume until reaching 20% of volume (14 ml.