Publications by authors named "Thyago Oliveira Rodrigues"
Article Synopsis
- Previous research indicates that being overweight or obese can disrupt brain function during critical developmental phases, but more studies are needed on how immediate overnutrition affects serotonin in the brain.
- This study investigates how altering serotonin levels with fluoxetine treatment in overnourished rats impacts oxidative stress and inflammatory markers in their brainstem and hypothalamus.
- Findings suggest that overnutrition in early life leads to harmful changes in brain chemistry, but fluoxetine treatment can counteract some of these negative effects, supporting healthier brain development.
Overweight during development dysregulates cellular metabolism and critical genes that control food intake in the prefrontal cortex.
Severina Cassia de Andrade Silva Maria Daniele Teixeira de Lemos Osmar Henrique Dos Santos Junior Thyago Oliveira Rodrigues Tercya Lucidi Silva
Physiol Behav
March 2024
Backgrounds And Aims: Childhood obesity is increasing substantially across the world. The World Obesity Federation (WOF) and World Health Organization (WHO) predicted that in 2030 > 1 billion people will be obese, and by 2035 over 4 billion will reach obesity worldwide. According to WHO, the world soon cannot afford the economic cost of obesity, and we need to act to stop obesity acceleration now.
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