Persistent organochlorine pollutants in different bivalve species from central Vietnamese coasts: Concentrations, profiles, and biota-sediment accumulation factors.

Concentrations of typical persistent organochlorine pollutants (POCPs) like organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) in five bivalve species collected from central Vietnamese coasts were determined to provide insights into spatial distribution and bioaccumulation characteristics of these substances. Concentrations of pollutants decreased in the order: PCBs (median 14.6; range 1.

Insight into heavy metal chemical fractions in ash collected from municipal and industrial waste incinerators in northern Vietnam.

This investigation involved the collection of fly ash and bottom ash specimens from seven waste incinerators situated in the northern provinces of Vietnam, aimed at assessing the composition and distribution patterns of five chemical fractions of heavy metals (Pb, Cr, As, Cd Cu, and Zn) present in incinerator waste ash. The outcomes reveal that fly ash exhibited a relatively elevated concentration of industrial waste metals (25-66%) such as As, Cd, and Pb primarily in exchangeable (F1) and carbonate fractions (F2), which are mobile forms susceptible to environmental dissolution and consequential bioaccumulation posing health risks to humans. The predominant states of the metals Cr, Cu, and Zn were identified as residual, Fe-Mn oxide, and carbonate, respectively, with their relative proportions showing minimal variation.

Response Methodology Optimization and Artificial Neural Network Modeling for the Removal of Sulfamethoxazole Using an Ozone-Electrocoagulation Hybrid Process.

Removing antibiotics from water is critical to prevent the emergence and spread of antibiotic resistance, protect ecosystems, and maintain the effectiveness of these vital medications. The combination of ozone and electrocoagulation in wastewater treatment provides enhanced removal of contaminants, improved disinfection efficiency, and increased overall treatment effectiveness. In this work, the removal of sulfamethoxazole (SMX) from an aqueous solution using an ozone-electrocoagulation (O-EC) system was optimized and modeled.

Chemical constituents from the heterotrophic marine microalgae sp. SC145 and their antimicrobial activities.

One new indol, -methoxymethyltryptophol (), one new phenolic, (2 )-2-(4-hydroxyphenyl)ethyl 2-hydroxy-3-phenylpropanoate () and fifteen known compounds () were isolated from the methanol extract of the fermentation of marine microalgae sp. SC145. Their structures were elucidated by 1D-, 2D-NMR spectroscopic analysis, HR-ESI-MS, quantum chemical calculation methods and by comparing their NMR data with those reported in the literature.

Synthesis, Anti-Influenza H1N1 and Anti-Dengue Activity of A-Ring Modified Oleanonic Acid Polyamine Derivatives.

A series of sixteen A-ring modified (2,3-indolo-, 2-benzylidene) oleanonic acid derivatives, holding some cyclic amines, linear polyamines and benzylaminocarboxamides at C28, has been synthesized and screened for antiviral activity against influenza A/PuertoRico/8/34 (H1N1) and Dengue virus serotypes of DENV-1, -2, -3, -4. It was found that 28-homopiperazine and 3--phthalyl amides of oleanonic acid demonstrated high potency with selectivity index SI 27 (IC 21 μM) and 42 (IC 12 μM). Oleanonic acid aminoethylpiperazine amide and C-azepano-erythrodiol appeared to be the most effective compounds against DENV-1 (ICs 67 and 107 μM) and -2 (ICs 86 and 68 μM correspondingly) serotypes.

Childhood encephalitis in the Greater Mekong region (the SouthEast Asia Encephalitis Project): a multicentre prospective study.

Background: Encephalitis is a worldwide public health issue, with a substantially high burden among children in southeast Asia. We aimed to determine the causes of encephalitis in children admitted to hospitals across the Greater Mekong region by implementing a comprehensive state-of-the-art diagnostic procedure harmonised across all centres, and identifying clinical characteristics related to patients' conditions.

Methods: In this multicentre, observational, prospective study of childhood encephalitis, four referral hospitals in Cambodia, Vietnam, Laos, and Myanmar recruited children (aged 28 days to 16 years) who presented with altered mental status lasting more than 24 h and two of the following minor criteria: fever (within the 72 h before or after presentation), one or more generalised or partial seizures (excluding febrile seizures), a new-onset focal neurological deficit, cerebrospinal fluid (CSF) white blood cell count of 5 per mL or higher, or brain imaging (CT or MRI) suggestive of lesions of encephalitis.

Anti-Dengue Screening on Several Vietnamese Medicinal Plants: Experimental Evidences and Computational Analyses.

Worldwide, medicinal plants have been known for economic and geographical advantages, thus possibly holding potentiality against dengue hemorrhagic fever. The methanol/water extracts from different parts of fourteen Vietnam-based plant species were subjected for experimental screening on anti-dengue activity using baby hamster kidney cells (BHK21) and plaque reduction neutralisation test (PRNT). Firstly, the methanol/water extracts were tested against serotype dengue virus DENV-1.

Chemical Composition Analysis and Antioxidant Activity of Monofloral Honeys from Vietnam.

Monofloral honey samples () from Vietnam were determined for their chemical compositions. This is the first report on the chemical composition and antioxidant activity of coffee honey from Vietnam. These samples were characterized by their high contents of total and reducing sugars, total phenolic contents, and total flavonoid contents.

Dogs as Sentinels for Flavivirus Exposure in Urban, Peri-Urban and Rural Hanoi, Vietnam.

Diseases caused by flaviviruses, including dengue fever and Japanese encephalitis, are major health problems in Vietnam. This cross-sectional study explored the feasibility of domestic dogs as sentinels to better understand risks of mosquito-borne diseases in Hanoi city. A total of 475 dogs serum samples from 221 households in six districts of Hanoi were analyzed by a competitive enzyme-linked immunosorbent assay (cELISA) for antibodies to the pr-E protein of West Nile virus and other flaviviruses due to cross-reactivity.

Vγ9γδ T Cell Induction by Human Umbilical Cord Blood Monocytes-Derived, Interferon-α-Stimulated Dendritic Cells.

Dendritic cells (DC) are professional antigen-presenting cells that activate T cells to kill cancer cells. The extracellular products of DCs have also been reported to perform the same function. In this study, we examined the differentiation of umbilical cord blood monocytes into DCs in the presence of GM-CSF, and interferon (IFN)-α.

Contamination status and temporal trends of persistent toxic substances in sediment cores from coastal areas of central Vietnam.

Residue concentrations of organochlorine pesticides (OCPs), polychlorinated biphenyls (PCBs), and polybrominated diphenyl ethers (PBDEs) were measured in sediment core samples from two estuary areas of central Vietnam to elucidate recent status and temporal trends of pollution based on the depth profiles. Concentrations of PCBs, PBDEs, and endosulfan compounds were generally higher than those of the remaining OCPs. Peak concentrations of OCPs were found in the sediment layers corresponding to the late 1950s to the early 1980s, implying the intensive application of these insecticides in Vietnam during such periods.

Addition of Partial Envelope Domain II into Envelope Domain III of Dengue Virus Antigen Potentiates the Induction of Virus-Neutralizing Antibodies and Induces Protective Immunity.

Dengue virus (DENV) comprises four serotypes in the family and is a causative agent of dengue-related diseases, including dengue fever. Dengue fever is generally a self-limited febrile illness. However, secondary infection of patients with a suboptimal antibody (Ab) response provokes life-threatening severe dengue hemorrhagic fever or dengue shock syndrome.

Plans for Nationwide Serosurveillance Network in Vietnam.

In recent years, serosurveillance has gained momentum as a way of determining disease transmission and immunity in populations, particularly with respect to vaccine-preventable diseases. At the end of 2017, the Oxford University Clinical Research Unit and the National Institute of Hygiene and Epidemiology held a meeting in Vietnam with national policy makers, researchers, and international experts to discuss current seroepidemiologic projects in Vietnam and future needs and plans for nationwide serosurveillance. This report summarizes the meeting and the plans that were discussed to set up nationwide serosurveillance in Vietnam.

Emission of Unintentionally Produced Persistent Organic Pollutants from Some Industrial Processes in Northern Vietnam.

Concentrations of PCDD/Fs, dioxin-like PCBs (dl-PCBs), PeCB and HCB were determined in flue gas, fly ash and bottom ash samples collected from brick production, steel production, and zinc production plants, an industrial waste incinerator and a medical waste incinerator in northern Vietnam to understand the contamination levels, accumulation patterns and extent of emission. Total TEQs concentrations of PCDD/Fs and dl-PCBs in flue gas and ash samples from these industrial plants ranged from 0.304 to 50.

Increase of Fungal Pathogenicity and Role of Plant Glutamine in Nitrogen-Induced Susceptibility (NIS) To Rice Blast.

  Modifications in glutamine synthetase OsGS1-2 expression and fungal pathogenicity underlie nitrogen-induced susceptibility to rice blast. Understanding why nitrogen fertilization increase the impact of many plant diseases is of major importance. The interaction between and rice was used as a model for analyzing the molecular mechanisms underlying Nitrogen-Induced Susceptibility (NIS).