Publications by authors named "Thuy Linh Hoang"
We aimed to elucidate the toxic effects and biological activities of 3-phenoxybenzoic acid (3PBA) and its metabolite products. Numerous methods were used to identify the toxic effects and biological activities of 3PBA, including PASS online, molecular docking, ADMETlab 2.0, ADMESWISS, MetaTox, and molecular dynamic simulation.
View Article and Find Full Text PDFDiabetes mellitus remains a major global health issue, and great attention is directed at natural therapeutics. This systematic review aimed to assess the potential of flavonoids as antidiabetic agents by investigating their inhibitory effects on α-glucosidase and α-amylase, two key enzymes involved in starch digestion. Six scientific databases (PubMed, Virtual Health Library, EMBASE, SCOPUS, Web of Science, and WHO Global Index Medicus) were searched until August 21, 2022, for in vitro studies reporting IC values of purified flavonoids on α-amylase and α-glucosidase, along with corresponding data for acarbose as a positive control.
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- SDSE (Streptococcus dysgalactiae subspecies equisimilis) is linked to serious infections like cellulitis and streptococcal toxic shock syndrome, particularly affecting the elderly and diabetics, but its pathogenic mechanisms are poorly understood.
- The enzyme HylD from SDSE degrades hyaluronate more effectively than similar enzymes from other streptococci, particularly under conditions found in infected skin; it may play a crucial role in the bacterium's ability to thrive in such environments.
- Research indicates that infection with SDSE leads to significant neutrophil infiltration, suggesting that HylD and another enzyme (UGL) could be essential for the bacteria’s nutrient acquisition and pathogenicity, although
The free and protein-bound ceramides of dog stratum corneum (SC) were analyzed by thin-layer chromatography after tape stripping of the abdomen of five dogs. The sphingoid bases were identified by gas-liquid chromatography as sphingosine, phytosphingosine, and 6-hydroxysphingosine. Electrospray ionization-ion trap mass spectrometry was used to characterize the protein-bound ceramides containing sphingosine and omega-hydroxy long-chain fatty acids.
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