Subgingival 0.75% boric acid vs 1% povidone-iodine adjunctive to subgingival instrumentation in stage II and III periodontitis-A double-blind randomized clinical trial.

Purpose: To compare the effects of subgingival irrigation with 0.75% boric acid (BA) and 1% povidone-iodine (PVP-I) as an adjunct to scaling and root planing (SRP) on clinical and microbiologic parameters in the management of patients with periodontitis after a 12-month follow-up.

Methods: Sixty systemically healthy individuals diagnosed with periodontitis were included in this double-blind randomised clinical trial.

Comparison of Antimicrobial Activity against between Advanced Platelet-Rich Fibrin and Injectable Platelet-Rich Fibrin.

Platelet-rich fibrin (PRF) obtained via low-speed centrifugation has antimicrobial properties. This study was conducted to evaluate the effectiveness of advanced platelet-rich fibrin plus (A-PRF+) and injectable platelet-rich fibrin (I-PRF), obtained from patients with different periodontal states, against . A-PRF+ and I-PRF samples were obtained from venous blood of 60 subjects divided equally into three groups: periodontitis, gingivitis, and healthy gingiva groups.

Antimicrobial effect against of advanced and injectable platelet-rich fibrin from patients with periodontal diseases versus periodontally healthy subjects.

Objectives: Advanced platelet-rich fibrin (A-PRF+) and injectable platelet-rich fibrin (i-PRF) have recently been developed and used in periodontal therapy. Few studies have contrasted the antibacterial effectiveness of these autologous materials derived from individuals with healthy gums, gingivitis, and periodontitis. This study aimed to compare the antimicrobial effects of these PRF materials against the periodontal pathogenic bacterium () in patients with different periodontal conditions.

Nonsurgical periodontal treatment improved the type 2 diabetes mellitus status in smokers: A randomized controlled trial.

Aim: Type 2 diabetes mellitus (T2D) and periodontal disease have bilateral associations. The effect of periodontal treatment on T2D patients who smoke is scarce. This study aimed to assess the effect of nonsurgical periodontal treatment (NSPT) in periodontitis smokers with T2D for a duration of 6 months of follow-up.

INTRABONY DEFECT TREATMENT WITH PLATELET-RICH FIBRIN, GUIDED TISSUE REGENERATION AND OPEN-FLAP DEBRIDEMENT: A RANDOMIZED CONTROLLED TRIAL.

Objective: To comparatively assess the outcomes of the treatment of periodontal intrabony defects with platelet-rich fibrin (PRF) combined with open-flap debridement (OFD), guided tissue regeneration (GTR) or OFD alone based on clinical, radiographic, and wound healing parameters for 12 months of follow-up.

Materials And Methods: Ninety intrabony defects were randomly divided into 3 different groups and treated as group 1 (PRF + OFD), group 2 (GTR), or group 3 (OFD alone). Clinical parameters, including the plaque index, gingival index, bleeding on probing, probing depth (PD), clinical attachment loss (CAL), and tooth mobility were assessed at 3, 6, and 12 months.

Morphological features of smile attractiveness and related factors influence perception and gingival aesthetic parameters.

Introduction: In addition to understanding the basic standards of a smile and patient's opinion, dentists should take into account smile aesthetics, an essential factor for optimal outcomes. This study aimed to evaluate the factors that affect the perception of an aesthetic smile and determine its morphological characteristics and measure the gingival aesthetic parameters.

Methods: In all, 200 Vietnamese aged 18-35 years were recruited to have their spontaneous smiles captured.

Comparison of Subgingival Irrigation Effect of Boric Acid 0.5% and Povidone-Iodine 0.1% on Chronic Periodontitis Treatment.

Purpose: To comparatively evaluate the effect of a 5% boric acid (BA) irrigant on periodontal condition, bacterial level and oral neutrophil numbers with a 1% povidone iodine (PVP-I) irrigant as an adjunct to scaling and root planing (SRP) in chronic periodontitis (CP) treatment.

Materials And Methods: A single-masked, randomised clinical trial with 36 CP patients was conducted at the Faculty of Odonto-Stomatology, University of Medicine and Pharmacy, Ho Chi Minh City, Vietnam. Subjects were randomly divided into two treatment groups: 1) SRP plus PVP-I 0.

Periodontal Status of the Adjacent Second Molar after Impacted Mandibular Third Molar Surgical Extraction.

Objective: The purpose of this study was to evaluate the change in periodontal status of the adjacent second molar of the impacted mandibular third molar after surgical extraction and its association with the third molar condition in the presurgical stages, including position, eruption level, and local complications.

Materials And Methods: The study was based on a 6-month follow-up of 38 patients (19 males and 19 females; Mean age: 21.89 ± 2.

In vitro characteristics of human periodontal ligament stem cells incubated with boric acid.

Objectives: To evaluate the influence of boric acid (BA) on various aspects of the human periodontal ligament stem cells (hPDLSCs), including proliferation, migration, and adhesion.

Methods: BA was prepared at increasing concentrations of 0.5%, 0.

Antimicrobial Effect of Platelet-Rich Plasma against .

Aim: The aim of our study was to evaluate whether there was a difference in antimicrobial effect between the PRP of healthy volunteers and that of patients with chronic periodontitis against which was fresh cultured from subgingival plaque.

Methods: Subgingival plaque of patients with moderate and severe chronic periodontitis was collected to isolate . The PRP of four individuals with healthy periodontium and four patients with moderate and severe periodontitis were collected with a specific kit using a two-centrifuge procedure, and then, the antibacterial properties against were tested, through their minimum inhibitory concentration (MIC), adhesion resistance assay, and biofilm susceptibility assay.

Evaluation of Proliferation and Migration Behaviour of Human Bone Marrow-Derived Mesenchymal Stem Cells in Presence of Platelet-Rich Plasma.

Objective: To access the effects of platelet-rich plasma (PRP) on the behaviour of human bone marrow-derived mesenchymal stem cells (hBMSCs), including proliferation and migration.

Methods: PRP was diluted with DMEM/F12, resulting in concentrations of 1%, 2%, and 5%. The proliferation of hBMSCs was examined by 2 methods: cell-number counting with the haemocytometer method and the colony-forming unit-fibroblast (CFU-F) assay.

An Update on Anti-CD137 Antibodies in Immunotherapies for Cancer.

The selective expression of CD137 on cells of the immune system (e.g., T and DC cells) and oncogenic cells in several types of cancer leads this molecule to be an attractive target to discover cancer immunotherapy.

Dental condition and salivary characteristics in Vietnamese patients with chronic kidney disease.

Objectives: To determine the dental status and salivary characteristics and to analyse the correlation between creatinine clearance with DMFT index and salivary flow rate in Vietnamese patients with chronic kidney disease (CKD).

Methods: This study was conducted on 111 CKD and 109 non-CKD patients. The socio-demographic characteristics associated with dental habits and xerostomia status were recorded from a self-administered questionnaire.

Factors related to dental caries in 10-year-old Vietnamese schoolchildren.

Background: In Vietnam, research is required to provide a clearer understanding of the factors associated with dental caries. This will allow paediatric dentists and physicians to provide appropriate care to children.

Aim: To determine the factors related to dental caries and to evaluate the association between dental caries and nutritional status in 10-year-old schoolchildren.

Efficacy of chlorine dioxide mouthwash in reducing oral malodor: A 2-week randomized, double-blind, crossover study.

The aim of this clinical trial was to assess the inhibitory effects of a mouthwash containing 0.1% ClO used for 2 weeks on oral malodor, periodontal and salivary parameters, tongue coating, and Gram-negative and Gram-positive bacteria in saliva. Thirty-nine subjects with oral malodor were randomly assigned into two groups.

Periodontal status of anterior teeth following clinical crown lengthening by minimally traumatic controlled surgical extrusion.

Background/aims: The number of fractured anterior teeth following trauma has been increasing while not every patient is able to afford a dental implant instead of maintaining the injured tooth. Thus, a tooth conservation solution is required to place an aesthetic and functional restoration without biologic width violation. The aim of this study was to evaluate the effectiveness of minimally traumatic controlled surgical extrusion in fractured anterior teeth crown lengthening by assessing the periodontal status through clinical examination and radiographs.

Effects of platelet-rich plasma on human gingival fibroblast proliferation and migration in vitro.

Objective: This study evaluated the influence of platelet-rich plasma (PRP) on the behaviour of human gingival fibroblasts (hGFs), including fibroblast proliferation, migration and colony formation.

Methods: PRP was obtained from the human peripheral blood of a healthy volunteer and then was diluted into platelet concentrations of 1%, 2% and 5%. The proliferation of hGFs was determined by two methods: (1) Cell-number counting with a haemocytometer method at days 1, 3, 5 and 7; (2) Colony-forming unit-fibroblast (CFU-F) assay at 2 weeks.

The interaction among obesity, Type 2 diabetes mellitus, and periodontitis in Vietnamese patients.

To examine the relationship between obesity, Type 2 diabetes, and periodontal disease in Vietnamese patients. The sample included 712 patients aged 18 years or older who first visited the Institute of Traditional Medicine, Ho Chi Minh City. All participants completed a questionnaire and underwent anthropometric index measurements for obesity (height, weight, waist, and hip circumferences) and had their body fat percentage measured.

Dental and periodontal problems of elderly people in Vietnamese nursing homes.

Objective: To determine the oral health status and treatment needs of elderly residents in Vietnamese nursing homes.

Methods: This study was conducted among 360 men and 431 women with a mean age of 72.9 ± 9.

Validation of the salivary urea and creatinine tests as screening methods of chronic kidney disease in Vietnamese patients.

Objectives: The aims of this case control study were to correlate the serum and salivary urea as well as creatinine levels; and to evaluate salivary urea and creatinine as noninvasive alternatives to serum for creatinine estimation in chronic kidney disease (CKD) patients.

Methods: Blood and saliva samples were collected from 112 CKD patients and 108 subjects without CKD for quantitative analysis of urea and creatinine. Spearman's correlation coefficients between salivary and serum urea as well as creatinine were obtained.

Risk factors of periodontal disease in Vietnamese patients.

Aim: The aim of the present study was to assess the association of periodontitis with dental and smoking behaviors, self-perception of oral status, dental knowledge, and obesity in Vietnamese patients.

Methods: A cross-sectional study was conducted on 367 adults who first visited the Faculty of Odonto-Stomatology, University of Medicine and Pharmacy, Ho Chi Minh City, Vietnam. Information on demographic characteristics, dental and smoking behaviors, self-perception of oral status, dental knowledge, and nutritional status was investigated by a self-administered questionnaire.

Relationship of a turbidity of an oral rinse with oral health and malodor in Vietnamese patients.

Aim: In the present study, the relationship between the turbidity of mouth-rinse water and oral health conditions, including oral malodor, in patients with (n = 148) and without (n = 231) periodontitis was examined.

Methods: The turbidity of 20 mL distilled water that the patients rinsed in their mouths 10 times was measured using a turbidimeter. Oral malodor was evaluated using an organoleptic test and Oral Chroma.

Factors affecting oral malodor in periodontitis and gingivitis patients.

Aim: To examine the associations between oral health status, the presence of N-benzoyl-DL-arginine-2-naphthylamide-positive bacteria, and oral malodor in periodontal patients.

Methods: A total of 137 periodontitis and 80 gingivitis patients were included in the study. Oral malodor was measured by an organoleptic test and the OralChroma.

Comparison between self-perceived and clinical oral malodor.

Objectives: The aims were to compare self-perceived with clinical oral malodor and to examine risk factors of oral malodor.

Study Design: The study was performed on 565 dental patients. Information on sociodemographics, dental health behavior, and self-perceived oral malodor was collected.

Comparison between self-estimated and clinical oral malodor.

Objectives: The aims were to evaluate the validity of patients' self-estimation and clinical diagnosis of oral malodor and to examine the relationship of oral malodor with oral health status.

Methods: The subjects were 252 patients (mean age 43.7 ± 10.