Publications by authors named "Thulasi Radhakrishnan"

The present study delves into the evolution of traditional Ayurvedic oil preparations through innovative strategies to develop advanced gel formulations, aiming at amplifying their therapeutic efficacy. Ayurvedic oils have a rich historical context in healing practices, yet their conversion into contemporary gel-based formulations represents a revolutionary approach to augment their medicinal potential. The primary objective of this transformation is to leverage scientific advancements and modern pharmaceutical techniques to enhance the application, absorption, and overall therapeutic impact of these traditional remedies.

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Urbanization has resulted in a surge in municipal solid waste (MSW) generation, posing critical waste management challenges in urban areas. To tackle this issue, we introduce a novel approach for mapping garbage vulnerability zones (GVZ) in Coimbatore City, India, combining the analytic hierarchy process (AHP) and Geographic Information System (GIS). Seven criteria, including per capita waste generation, open dumping, land use land cover, road/railway networks, and population, were integrated and analyzed in GIS.

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Background: Hypertension is a cardiovascular disorder that is an incurable clinical condition. It requires lifelong therapy for its management along with long terms application of synthetic drugs associated with severe toxicity in multiple organs. However, the therapeutic application of herbal medicines to treat hypertension has gained considerable attention.

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Reduced graphene oxide-yttria nanocomposite (rGO:Y) is applied as electrochemical genosensor platform for ultrahigh sensitive detection of breast cancer 1 (BRCA1) gene for the first time. The sensor is based on the sandwich assay in which gold nanoparticle cluster labeled reporter DNA hybridize to the target DNA. Glassy carbon electrode modified with rGO-yttria serves as the immobilization platform for capture probe DNA.

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