Publications by authors named "Thu-Hang Thi Ho"
Combined Gap-Polymerase Chain Reaction and Targeted Next-Generation Sequencing Improve α- and β-Thalassemia Carrier Screening in Pregnant Women in Vietnam.
Tuan-Thanh Lam Doan-Tu Nguyen Quang Thanh Le Duy-Anh Nguyen Diem-Tuyet Thi Hoang Van Thong Nguyen Thu-Hang Thi Ho Trung Hoanh Tran Viet Thang Ho Phuoc Ba Hoang Hoai Thanh Nguyen Manh Hoan Nguyen Hong-Thuy Thi Dao Hoa Giang Hoai-Nghia Nguyen
Hemoglobin
July 2022
Article Synopsis
- Vietnam has a significant thalassemia issue, with a study of 5,880 pregnant women revealing a 13.13% carrier frequency for thalassemia.
- The breakdown of carriers included 7.82% for α-thalassemia and 5.31% for β-thalassemia, with common mutations identified in both types.
- The study highlights the effectiveness of combining next-generation sequencing with gap-PCR for comprehensive thalassemia screening, estimating that around 5,021 babies could be born with severe thalassemia in Vietnam each year.