Publications by authors named "Thorunn Gudmundsdottir"
The study describes the identification of type VI secretion systems (T6SSs) in Moritella viscosa, the aetiological agent of winter ulcer disease. Despite the availability of commercial vaccines, M. viscosa causes significant financial losses in salmonid farming.
View Article and Find Full Text PDFObjective: Increased morbidity and higher prevalence of medication use commonly coexists among the elderly. When managed appropriately, older patients can benefit from drug therapy. However, drug related problems are more frequent and more serious in the elderly.
View Article and Find Full Text PDFWe have previously reported suggestive linkage of type 2 diabetes mellitus to chromosome 10q. We genotyped 228 microsatellite markers in Icelandic individuals with type 2 diabetes and controls throughout a 10.5-Mb interval on 10q.
View Article and Find Full Text PDFWe previously mapped susceptibility to stroke to chromosome 5q12. Here we finely mapped this locus and tested it for association with stroke. We found the strongest association in the gene encoding phosphodiesterase 4D (PDE4D), especially for carotid and cardiogenic stroke, the forms of stroke related to atherosclerosis.
View Article and Find Full Text PDFArticle Synopsis
- Stroke is a complex disease with various subtypes and multiple secondary risk factors like hypertension and diabetes, which have their own genetic and environmental influences.
- Researchers conducted a genomewide search for genes that might increase susceptibility to common stroke forms by analyzing data from stroke patients in Iceland and a genealogy database, identifying 476 patients within 179 extended families.
- A significant discovery was made on chromosome 5q12, with a high LOD score indicating strong evidence for a genetic link to stroke; this region, named "STRK1," is novel and not previously associated with known stroke susceptibility loci.