Publications by authors named "Thorsten RieSS"
Article Synopsis
- Electroporation is a technique that uses electric pulses to temporarily open cell membranes, allowing molecules, especially small hydrophilic ones, to enter cells more easily.
- The study investigates how electrotransferred DNA moves within the cell to reach the nucleus, focusing on the cytoskeleton's role in this process through single-particle tracking experiments.
- Results show that DNA movement is actively facilitated by the cytoskeleton, with disruptions in actin and tubulin filaments decreasing the efficiency and speed of this transport, while stabilization of these filaments does not improve DNA transport.
Plateau bursting is typical of many electrically excitable cells, such as endocrine cells that secrete hormones and some types of neurons that secrete neurotransmitters. Although in many of these cell types the bursting patterns are regulated by the interplay between voltage-gated calcium channels and calcium-sensitive potassium channels, they can be very different. We investigate so-called square-wave and pseudo-plateau bursting patterns found in endocrine cell models that are characterized by a super- or subcritical Hopf bifurcation in the fast subsystem, respectively.
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