The study investigates how irradiation affects implant stability in the jawbone of minipigs, comparing irradiated and non-irradiated areas.
Initial implant stability was similar in both groups, but over time, stability decreased more in irradiated bones, indicating the impact of reduced bone vitality.
Despite initial decreases in stability, there was a slight stabilization or increase in implant stability by the end of the study period in both groups.
The study aimed to confirm that laser Doppler flowmetry (LDF) reliably assesses the vascularity of maxillary and mandibular bones, finding reduced vascularity in irradiated bones compared to nonirradiated ones.
After extracting teeth from six minipigs, three were irradiated, and LDF measured blood flow around drilled holes in the jawbone, revealing less vascularization in irradiated areas, particularly in the mandible.
The findings support the use of LDF for evaluating bone vascularity, suggesting a need for further research on its application in humans, especially those post-radiation therapy for head and neck cancer.