Half a century of computer methods and programs in biomedicine: A bibliometric analysis from 1970 to 2017.

Background And Objective: Computer Methods and Programs in Biomedicine (CMPB) is a leading international journal that presents developments about computing methods and their application in biomedical research. The journal published its first issue in 1970. In 2020, the journal celebrates the 50th anniversary.

Intravenous lacosamide in clinical practice-Results from an independent registry.

Purpose: This non-interventional study was conducted to evaluate the efficacy and tolerability of intravenous lacosamide (LCM-iv) under routine conditions in daily clinical practice as a prospective registry.

Methods: Patients with any type of seizure or epilepsy syndrome were recruited in 16 neurological and neuropediatric centers in Germany if the treating physician decided to administer LCM-iv for any reason. Observation time per patient was 10 days with daily documentation of LCM-iv administration, type and frequency of seizures, currently used drugs and doses, and adverse events.