Alendronate prevents femoral periprosthetic bone loss following total hip arthroplasty: prospective randomized double-blind study.

Following total hip arthroplasty (THA), femoral periprosthetic bone undergoes a remodeling process that results in bone loss in its proximal regions that may compromise the long-term outcome of THA. Periprosthetic bone loss mainly occurs during the first postoperative months. The question is whether a postoperative treatment with alendronate is effective in reducing periprosthetic bone loss and which doses and duration of treatment are required.

Bone strength influences periprosthetic bone loss after hip arthroplasty.

Unlabelled: Our primary question was whether bone strength at the time of surgery, reflected by the lumbar spine T-score and femoral cortical thickness, influences periprosthetic bone loss after a total hip arthroplasty. Using dual energy xray absorptiometry we preoperatively and postoperatively examined 38 consecutive patients having cementless total hip arthroplasties for their bone density. Bone strength was estimated using lumbar spine bone mineral density and the ipsilateral diaphyseal cortical thickness of the femur measured on radiographs.