Publications by authors named "Thorstein Gudmundursson"
Differences between cardiac troponin I vs. T according to the duration of myocardial ischaemia.
Aaron Shekka Espinosa Shafaat Hussain Amin Al-Awar Sandeep Jha Ahmed Elmahdy Thorstein Gudmundursson
Eur Heart J Acute Cardiovasc Care
June 2023
Article Synopsis
- The study investigates the levels of cardiac troponin T (hs-cTnT) and troponin I (hs-cTnI) during and after different durations of myocardial ischaemia (lack of blood flow) in both rats and human patients with heart attacks (STEMI).
- Results show that after short periods of ischaemia, hs-cTnI and hs-cTnT levels rise similarly, leading to a ratio of around 1, indicating non-necrotic cTn release.
- In contrast, longer ischaemia that results in heart tissue damage shows a significantly higher hs-cTnI/hs-cTnT ratio (3.6-5.5),