Bottom-up rather than top-down mechanisms determine mesocarnivore interactions in Norway.

Interactions among coexisting mesocarnivores can be influenced by different factors such as the presence of large carnivores, land-use, environmental productivity, or human disturbance. Disentangling the relative importance of bottom-up and top-down processes can be challenging, but it is important for biodiversity conservation and wildlife management. The aim of this study was to assess how the interactions among mesocarnivores (red fox , badger , and pine marten ) were affected by large carnivores (Eurasian lynx and wolf ), land cover variables (proportion of agricultural land and primary productivity), and human disturbance, as well as how these top-down and bottom-up mechanisms were influenced by season.

Altitude, latitude and climate zone as determinants of mountain hare () coat colour change.

Local adaptation to annually changing environments has evolved in numerous species. Seasonal coat colour change is an adaptation that has evolved in multiple mammal and bird species occupying areas that experience seasonal snow cover. It has a critical impact on fitness as predation risk may increase when an individual is mismatched against its habitat's background colour.

New insight into the composition of extracellular traps released by macrophages exposed to different types of inducers.

Neutrophil extracellular trap (NET) release plays a key role in many chronic disease settings, including atherosclerosis. They are critical to innate immune defence, but also contribute to disease by promoting thrombosis and inflammation. Macrophages are known to release extracellular traps or "METs", but their composition and role in pathological processes are less well defined.

Movement and habitat selection of a large carnivore in response to human infrastructure differs by life stage.

Background: The movement extent of mammals is influenced by human-modified areas, which can affect population demographics. Understanding how human infrastructure influences movement at different life stages is important for wildlife management. This is true especially for large carnivores, due to their substantial space requirements and potential for conflict with humans.

Mapping the modification of histones by the myeloperoxidase-derived oxidant hypochlorous acid (HOCl).

Histones are critical for the packaging of nuclear DNA and chromatin assembly, which is facilitated by the high abundance of Lys and Arg residues within these proteins. These residues are also the site of a range of post-translational modifications, which influence the regulatory function of histones. Histones are also present in the extracellular environment, following release by various pathways, particularly neutrophil extracellular traps (NETs).

Smartphone app reveals that lynx avoid human recreationists on local scale, but not home range scale.

Outdoor recreation is increasing and affects habitat use and selection by wildlife. These effects are challenging to study, especially for elusive species with large spatial requirements, as it is hard to obtain reliable proxies of recreational intensity over extensive areas. Commonly used proxies, such as the density of, or distance to, hiking paths, ignore outdoor recreation occurring on other linear feature types.

Camera trap records of leucistic Eurasian badgers () in central Norway.

Coat coloration plays an important role in communication, camouflage, and sexual selection in animals. Genetic mutations can lead to anomalous colorations such as melanism and leucism, where animals appear, respectively, darker or lighter than normal. Reporting abnormal coloration in wild animals is an important first step to understand the distribution, prevalence, and potential fitness consequences of these rare events.

Human papillomavirus vaccination and all-cause morbidity in adolescent girls: a cohort study of absence from school due to illness.

Background: A growing body of evidence supports the safety of the human papillomavirus (HPV) vaccines. However, concerns about autonomic dysfunction syndromes and non-specific symptoms continue to linger. These conditions are not easily captured by traditional diagnostic classification schemes and call for innovative approaches to the study of vaccine safety which take more general measures of all-cause morbidity into account.

Association between quadrivalent human papillomavirus vaccination and selected syndromes with autonomic dysfunction in Danish females: population based, self-controlled, case series analysis.

Objective: To evaluate the association between quadrivalent human papillomavirus vaccination and syndromes with autonomic dysfunction, such as chronic fatigue syndrome, complex regional pain syndrome, and postural orthostatic tachycardia syndrome.

Design: Population-based self-controlled case series.

Setting: Information on human papillomavirus vaccinations and selected syndromes with autonomic dysfunction (chronic fatigue syndrome, complex regional pain syndrome, and postural orthostatic tachycardia syndrome) identified using ICD-10 (international classification of diseases, revision 10) diagnostic codes from Danish nationwide registers.

A cluster analysis of serious adverse event reports after human papillomavirus (HPV) vaccination in Danish girls and young women, September 2009 to August 2017.

BackgroundSuspected adverse events (AE) after human papillomavirus (HPV) vaccines include postural orthostatic tachycardia syndrome (POTS), chronic fatigue syndrome (CFS), complex regional pain syndrome (CRPS) and symptoms including headache and orthostatic intolerance.AimWe aimed to identify phenotypes of AEs after HPV vaccination, defined as patterns of AE terms (signs, symptoms, diagnoses), and to evaluate if identified phenotypes reflected previously suspected symptomatology or heightened public concerns over HPV vaccine safety since 1 January 2015.MethodsWe conducted a retrospective observational study using latent class cluster analysis of all serious AE reports (n = 963) reported by females residing in Denmark between September 2009 and August 2017.

Impact of school staff health on work productivity in secondary schools in Massachusetts.

Background: Healthy, productive employees are an integral part of school health programs. There have been few assessments of work productivity among secondary school staff. This study describes the frequency of 3 common health risk factors--obesity, depressive symptoms, and smoking--and their impact on work productivity in secondary school employees.

Modified condylotomy versus conventional conservative treatment in painful reciprocal clicking--a preliminary prospective study in eight patients.

Modified condylotomy may be relevant in severe painful reciprocal clicking of the temporomandibular joint (TMJ) where conservative treatment is insufficient. The effect of the modified condylotomy was analyzed and compared with conventional nonsurgical treatment in a randomized pilot study of eight patients, 19-44 years of age, with severe painful reciprocal clicking. Before and after treatment, assessments were performed by subjective reports, clinical recordings, and blinded evaluations of radiography and magnetic resonance imaging (MRI).

Cost savings associated with smoking cessation for low-income pregnant women.

Despite the many health risks associated with smoking during pregnancy, it remains a chief public health concern with a high prevalence evident at the local level. In Wisconsin, the First Breath program was developed to help pregnant smokers quit and served 424 women during its pilot phase in 2001 and 2002. This cost savings analysis included claims associated with First Breath enrollees who were identified within the Wisconsin Medicaid data warehouse.

Sentence intonation in textual context--supplementary data.

The experiment presented here is a sequel to a previous investigation [N. G. Thorsen, J.

Treatment of angina pectoris with pindolol: the significance of intrinsic sympathomimetic activity of beta blockers.

Although all beta blockers have been found to be effective in the symptomatic relief of angina pectoris, the importance of intrinsic sympathomimetic activity (ISA) has not been studied extensively. In a randomized, double-blind study, we administered equipotent doses of propranolol (10, 20, and 40 mg four times a day) and pindolol (2.5, 5, and 10 mg four times a day), a beta blocker with significant ISA, to 52 patients with angina.

On the variability in F0 patterning and the function of F0 timing in languages where pitch cues stress.

The basic property of pitch as a cue to linguistic stress is fundamental frequency (F0) change. That leaves room for a lot of variation: in the direction of the change, the amount of change, and its exact coordination with the stressed syllable. Examples (from the literature) from a number of languages and dialects attest that they do indeed exhibit quite striking differences in the stress/F0 relationship.

A study of perception of sentence intonation--evidence from Danish.

Ten subjects identified 15 Danish utterances by a human speaker, differing only in their fundamental frequency (F0) course, as being either declarative, nonfinal, or interrogative (forced choice). Responses are closely correlated with F0: the most steeply falling intonation contours are identified as being declarative, the least falling ones as being interrogative, and contours in the middle of the continuum as being nonfinal. Several mutually interdependent parameters in the F0 course may account for the results, the two most powerful one, however, being the levels of the last stressed and the succeeding unstressed syllable, respectively, in the utterance.