Retrospective review of work transition narratives: Advancing occupational perspectives and strategies.

Background: In 2009 the journal WORK commenced a new column for the publication of Work Transition Narratives. Fourteen persons with lived experience published their narratives on approaches that helped them through work disruptions and change.

Objective: A review of the articles was conducted to understand how people navigated challenges and obstacles and made sense of their in-transition experiences to return to work or to find new employment.

Determination of the target population in early benefit assessments in Germany: challenges for non-small-cell lung cancer.

Objectives: Dossiers submitted for early benefit assessments in Germany also provide information on the precise determination of the target population (patients eligible for a drug). The situation is complex for non-small-cell lung cancer (NSCLC) due to highly specific therapeutic indications. Our aim was to compare the different methodological steps applied to determine the target population in dossiers on drugs for NSCLC.

Can Routine Data be used to Determine the Target Population of Patients with Type 2 Diabetes in Early Benefit Assessments in Germany?

Objectives: Since 2011, early benefit assessment of all new drugs launched in Germany is mandatory. The exact determination of the appropriate target population (i. e.

One-year prospective three-center study comparing the outcome of a "soft bone implant" (prototype Mk IV) and the standard Brånemark implant.

Background: Oral implant treatment ad modum Brånemark has been used for decades in the rehabilitation of edentate and partially dentate patients. Posterior jaw regions frequently exhibit bone of poor texture, and it is often difficult to obtain primary stability. Thus, it may prove beneficial to deviate from the original protocol and to use implants with a modified design, for example, with a slightly tapered geometry.

Reviewing asthma and anxiety.

The main characteristic of asthma is sudden and unexpected attacks of impaired breathing. Both the attacks themselves and the prospect of attacks generate much anxiety amongst patients. Several different forms of anxiety can be identified which vary in intensity and the situations in which they appear.

Perception of dyspnea during histamine- and methacholine-induced bronchoconstriction.

Background: Perception of dyspnea is poorly related to bronchoconstriction and may be influenced by distinct psychophysiologic stimuli.

Objective: This study compared the perceived psychophysiologic changes during histamine- and methacholine-induced bronchoconstriction using verbal as well as nonverbal assessment techniques.

Methods: Perception of dyspnea was studied during induced bronchoconstriction in 40 atopic subjects randomly ascribed to either histamine (n = 20) or methacholine (n = 20) bronchial challenge.

Creation of new bone by an osteopromotive membrane technique: an experimental study in rats.

Domes, 5 and 8 mm in diameter, were made of expanded polytetrafluorethylene membrane with different degrees of stiffness and internodal distance. The domes were placed on denuded calvarial bones of rats and covered by the skin and periosteal flaps. Histologic evaluation 9 to 16 weeks after surgery showed the formation of various amounts of new bone on the calvarial bone surface inside the domes.

Repair of complete atrioventricular canal. 15 year's experience.

Corrective surgery for complete atrioventricular canal was performed over a 15-year period on 72 patients, 49 of whom had Down's syndrome: 46 were without major associated cardiac anomalies and 15 had previously undergone pulmonary artery banding. The pressures in the right and left ventricles equilibrated in 77% of the patients. The early mortality rate was 18% and the late mortality 7%.

Effect of metabolic control and duration on exercise-induced albuminuria in diabetic teen-agers.

Nineteen type I diabetic teen-agers without clinical signs of nephropathy with a duration of diabetes varying from 3 to 16.8 years were examined by a standardized exercise test for analysis of urinary excretion of albumin and beta 2-microglobulin. The patients were studied both in poor and improved (but not perfect), metabolic control as defined by HbA1c and blood glucose profiles, and the values were compared to those of 14 age-matched healthy controls.

Ventilation-perfusion relationships in children.

Ventilation-perfusion relationships (Va/Q) were studied in nine lung-healthy children, 7-15 years old, in whom a diagnostic heart catheterization was performed. VA/Q was assessed by a multiple inert-gas elimination technique. In subjects above 10 years of age, single, narrow modes of ventilation and perfusion were seen centred upon a VA/Q ratio of one.

Skeletal muscle fibre types and sizes in anorexia nervosa patients.

Fibre type composition and fibre areas in skeletal muscle of anorexia patients were studied on biopsies from the m. quadriceps femoris in five male and five females, whose body weight was 2-3.5 SDs less than expected from the normal weight/height relationship.

New ways of treating children with congenital heart disease.

The rapid development of new methods of diagnosis and treatment of children with congenital heart disease is revealed. Because of decreasing death risk open heart surgery is now available already in infancy. Early corrective surgery has advantages to two-step repair.

Prolonged exercise in adolescent boys with juvenile diabetes mellitus. Circulatory and metabolic responses in relation to perceived exertion.

Seven well-trained adolescent boys with juvenile diabetes mellitus were studied. They were non-ketotic and performed a 60 min exercise in the afternoon at an average intensity of 58% of maximal working capacity. Blood glucose, blood lactate, plasma levels of insulin, C-peptide and 3-hydroxybutyrate, oxygen uptake and respiratory quotient were determined.

Exercise testing with special reference to children with diabetes mellitus.

The purpose of exercise testing in diabetes mellitus is to examine physical fitness and to motivate the patient to perform physical activity as a valuable part of the treatment. Different types of tests and ergometry are presented. The stepwise increase of workload at submaximal levels is recommended for diabetics as an annual test.

Right atrial-right ventricular anastomosis for correction of tricuspid atresia.

Previously reported methods for the correction of tricuspid atresia involve the use of conduits and/or valves. Since many of the younger patients will outgrow their conduits and the long-term durability of the valve prostheses is open to question, we have devised an operation in which the right atrial (RA) appendage is anastomosed to the right ventricle (RV) with the aid of a pericardial patch. The RV, if not too hypoplastic, is used as a pumping chamber and the pulmonary valve is in its normal position.

Long-term effect of previous swimtraining in girls. A 10-year follow-up of the "girl swimmers".

Thirty girls, studied in 1961 after 2.5 years of intensive swimtraining, were the subject of a follow-up for ten years. When last examined, seven and ten years after the original study, all the girls had given up swimtraining.

Total body potassium fat free weight and maximal aerobic power in children with anorexia nervosa.

Body composition and aerobic work performance have been studied in 5 boys and 10 girls suffering from anorexia nervosa. The average ages of the two groups of children were 15.4 (boys) and 15.

Limb circulation in anorexia nervosa.

Blood flow, skin temperature and blood pressure of the lower limbs and the effect of indirect, radiant heat on calf blood flow and leg skin temperature was determined in sixteen children with anorexia nervosa (group A) and fourteen healthy children (group H) of the same age and body height. Calf blood flow as measured by venous occlusion plethysmography. Arm blood pressure was obtained by tourniquet and toe pressure and digital plethysmograms by a strain-gauge.